Clinical trials
Major Noncardiac Surgery clinical trials
Below are recruiting major noncardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05728775RecruitingPhase 4
Comparing two anesthetics after major non-heart surgery
This trial compares the anesthesia medicines remimazolam and propofol during major surgery to see how patients do afterward. It may help guide which anesthetic is safer or leads to better recovery in higher-risk patients.
Hefei, AnhuiAges 45 years+ - NCT06957912Recruiting
Ear nerve stimulation for recovery after major surgery
This trial tests if stimulating a nerve in your ear (vagus nerve) before and after noncardiac surgery can improve your recovery. It's for adults aged 18 to 84 having planned or time-sensitive surgery lasting at least 2 hours.
Beijing, Beijing MunicipalityAges 18–85 - NCT06859892RecruitingPhase 4
Drug combo study for better sleep after major surgery
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
BeijingAges 18 years+ - NCT06802224RecruitingPhase 4
Medication to prevent kidney injury after major surgery
This study compares two medications given during surgery to see which one better protects the kidneys after the procedure. If you are having major non-cardiac surgery that lasts at least 2 hours and you need medication to support your blood pressure, this trial may be a good fit.
San Francisco, CaliforniaAges 18 years+ - NCT07335042Recruiting
Heart injury risk after major liver or bile duct surgery
This study looks at whether certain patients have heart muscle injury (called MINS) after major liver or bile duct surgery. If you are having this type of surgery, your doctors will check your heart with a special blood test before and after. The goal is to find out who is at risk and help prevent problems.
BeijingAges 18–85 - NCT05990790RecruitingPhase 4
Comparing anesthetics and their effect on confusion after surgery
This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.
InnsbruckAges 65 years+ - NCT05812248Recruiting
Tracking heart and blood vessel events after major non-heart surgery
This study follows people after major surgery to see what predicts heart and blood vessel problems later. It does not test a new drug; it mainly collects health information to help clinicians reduce risk.
Guangzhou, GuangdongAges 45 years+ - NCT06279000RecruitingPhase 3
Colchicine for heart risk during major non-heart surgery
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Sankt Gallen, Canton of St. GallenAges 45 years+ - NCT04934683Enrolling by invitationPhase 4
Medication study during major surgery to protect blood pressure
This trial tests how well an “induction agent” medication works during major surgery to help keep blood pressure stable. It may help prevent complications in people at higher risk, especially those staying overnight in the hospital.
Omaha, NebraskaAges 45 years+ - NCT06961630RecruitingEarly Phase 1
Heart protection after surgery
This trial tests if a personalized approach with blood thinners and statins can reduce heart risks after non-cardiac surgery. It is for adults 45 and older who had a heart injury during or after surgery.
New York, New YorkAges 45 years+ - NCT06519747Recruiting
Detecting irregular heartbeat after non-heart surgery
This trial uses a monitoring device to check for a common but often overlooked irregular heartbeat (atrial fibrillation) after non-cardiac surgery. The goal is to detect and treat it early to prevent complications like stroke.
Hamilton, OntarioAges 18–120
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Common questions
- Are there clinical trials for major noncardiac surgery?
- Yes. Clin2 currently lists 11 recruiting major noncardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a major noncardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a major noncardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.