Beta-blocker treatment for severe traumatic brain injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma clinical trials.
This trial tests whether a heart medication called a beta-blocker can help people who have had a severe traumatic brain injury. By reducing stress on the body, it may support recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Patient is between 18 and 65 years old
- Has a severe traumatic brain injury (Glasgow Coma Scale score of 8 or less)
- No pre-existing heart disease
- No conditions that prevent the use of beta-blockers
- The injury is not a penetrating head wound
- No prior brain issues or use of beta-blockers/clonidine before the injury
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to manage brain pressure after a severe head injury. The goal is to improve blood flow to the brain, which may help recovery.
This study tests a non-invasive device that measures pressure inside the skull (intracranial pressure) without needing surgery, to help doctors treat people with brain injuries or strokes in busy emergency rooms. The goal is to see if this simpler monitoring can improve care and outcomes.
This trial tests whether giving a beta blocker drug after a moderate or severe traumatic brain injury can improve recovery. It is for patients who have a brain injury but only minor or no other injuries.
This trial tests whether a common beta-blocker (metoprolol) can protect the heart from injury and reduce inflammation after a bleed in the brain (subarachnoid hemorrhage). It may help patients recover better after this type of stroke.
This study looks at patients with severe traumatic brain injury (TBI) who already need brain pressure or oxygen monitoring. Doctors want to see if certain tests can help predict how well someone might recover.
This study tests a special brain-monitoring system in the ICU for people with severe brain injuries. It aims to give doctors early warnings about changes in the brain and help predict recovery, which may improve treatment and outcomes.
Hear when a new Traumatic Brain Injury (TBI) Patients trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.