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NCT06908993Possibly a fitRecruiting

Tepotinib vs standard care for MET-mutated lung cancer

Advanced Non Small Cell Lung CancerMET Exon 14 Mutation

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a targeted pill called tepotinib against standard treatments for advanced lung cancer with a specific MET gene change. It is for people whose cancer has progressed after at least one prior therapy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
133 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your cancer has a specific change called MET exon 14 skipping mutation, found through a biopsy or blood test.
  • You must have had at least one prior cancer treatment (chemo or immunotherapy), but no more than two total prior treatments.
  • You can be active or need some help with daily activities (ECOG status 0, 1, 2, or 3).
  • You must have adequate kidney, liver, and blood cell counts as shown by routine lab tests.
  • You have not been treated before with a drug that targets MET (like crizotinib).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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