Study on autoimmune causes in sensory and autonomic disorders
Part of Bones, joints & muscles, Brain & nervous system clinical trials.
This study looks at whether the immune system (autoimmune) plays a role in conditions like Postural Tachycardia Syndrome (PoTS) and Fibromyalgia (FMS). It compares people with these conditions to healthy volunteers. The goal is to understand the causes and find better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old.
- You need to understand and agree to the study consent form.
- You must be available for scheduled visits and procedures.
- For PoTS: you must meet specific heart rate and blood pressure criteria from 2015 guidelines.
- For FMS: you need a diagnosis based on 2016 criteria, with a high impact score (over 50) and pain level (over 5.5).
- Healthy volunteers: you cannot have any diagnosed autoimmune, chronic pain, or dysautonomia condition.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two medications—guanfacine and cromolyn sodium—to see if they can help people with POTS who have symptoms that started after a specific trigger. It might help if you have not found relief from other treatments.
This study tests a non-invasive device that stimulates a nerve near your ear (called the tragus) to see if it can help manage POTS symptoms. It may be an option for people whose POTS has lasted more than 6 months and who do not have other serious health conditions.
This study tests simple body movements (like squeezing your legs or squatting) to see if they help control POTS symptoms. It may offer a non-drug way to manage dizziness and fast heart rate when standing.
This trial tests a gentle, non-invasive treatment for Postural Orthostatic Tachycardia Syndrome (POTS), a condition that causes a rapid heart rate when standing. It combines mild ear nerve stimulation with slow, paced breathing to see if it helps manage symptoms like dizziness and fatigue.
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
This study looks at why some people develop POTS (a condition that causes a fast heart rate and dizziness when standing) and if it's linked to how the brain and vagus nerve work together. It also includes people recovering from a serious infection and healthy volunteers for comparison.
Hear when a new Fibromyalgia (FM) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.