Clin2
NCT07044700Possibly a fitNot yet recruiting

Jardiance compared with standard heart failure medicines in Chinese patients

Heart Failure of Reduced Ejection Fraction (HFrEF)

Treatments studied

Part of Heart & circulation clinical trials.

This study looks at how well Jardiance (a medication for heart failure) works and how safe it is compared to other standard heart failure medicines in Chinese patients with a weak heart pump. It helps us understand which treatment works best in real life.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
5,000 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with heart failure with reduced ejection fraction, and your recent heart function test (ejection fraction) is 40% or lower.
  • You have had a blood test showing elevated heart strain markers (NT-proBNP >125 or BNP ≥35).
  • You are starting a new treatment for heart failure, either Jardiance (empagliflozin) or one of the standard heart failure medicines like ACE inhibitors, ARBs, ARNI, beta-blockers, or MRAs.
  • You have not taken any SGLT2 inhibitors (such as Jardiance) in the past 6 months.
  • Your body mass index (BMI) is lower than 45.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06669169Not yet recruiting· Phase 2
Herbal tablet for chronic heart failure from coronary disease

This trial tests whether a Chinese herbal tablet called Jia Shen can improve heart function and reduce symptoms in people with chronic heart failure caused by coronary heart disease. It aims to find a new option that may help you feel better and stay out of the hospital.

Tianjin, Tianjin Municipality
NCT07047508Not yet recruiting
Jardiance study for heart failure with preserved pumping function

This study looks at how well the medicine Jardiance works and how safe it is for people with a certain type of heart failure where the heart's pumping function is only slightly reduced or preserved. It aims to help doctors understand the medicine's real-world effects in Chinese patients.

NCT07038356Recruiting· Phase 3
Continuing empagliflozin during heart failure hospitalizations

This study tests whether continuing empagliflozin (a heart failure medicine) during a hospital stay for heart failure is beneficial compared to stopping it. Participation may help improve recovery and reduce complications.

Jena, Thuringia
NCT07331727Not yet recruiting
Heart fat targeted drug for improving atrial fibrillation outcomes

This study tests whether a medicine called dapagliflozin (usually used for diabetes) can reduce heart tissue changes in people with persistent atrial fibrillation. It is given along with the standard ablation procedure, aiming to improve the heart's electrical health and potentially make the procedure more effective.

Shanghai
NCT07465653Recruiting· Phase 1
Study of HJB647 for heart failure with reduced pumping ability

This trial tests a new medicine, HJB647, in people with heart failure who have a weak heart pump. It aims to see if the drug is safe and well-tolerated. You may qualify if your heart's pumping ability is reduced and you are on a specific standard therapy.

Bradenton, Florida
NCT06783166Recruiting· Phase 2/Phase 3
Comparing two medications for acute heart failure with fluid buildup

This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.

Al Mansurah

Hear when a new Heart Failure of Reduced Ejection Fraction (HFrEF) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.