Melatonin for sleep and brain health in cirrhosis
Treatments studied
Part of Brain & nervous system, Digestive system, Hormones & metabolism, Mental health clinical trials.
This study tests whether melatonin (a natural sleep hormone) can improve sleep and thinking abilities in people with cirrhosis and liver-related brain fog. It aims to see if better sleep leads to clearer thinking.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have cirrhosis (scarring of the liver) with signs of high pressure in the liver veins or a history of liver-related complications
- You have been diagnosed with hepatic encephalopathy (confusion or brain fog from liver disease) or have trouble with thinking and memory
- You have trouble sleeping most nights (score of 5 or more on a standard sleep questionnaire)
- You own a smartphone (iPhone with iOS 14+ or Android 8.0+) that can download the Oura app
- You are not currently taking melatonin 3 or more times a week, or you can stop taking it for the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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