Preventing seizures after severe head injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma clinical trials.
This trial tests whether giving medication right after a serious head injury can prevent early seizures. It may help people with certain types of brain injuries seen on CT scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a severe head injury (your Glasgow Coma Scale score was less than 10)
- Or your GCS score was 10 or higher but a CT scan showed brain injury like bleeding or a skull fracture
- Or you had a penetrating head injury (something went through your skull)
- You must not be pregnant
- You must not have had a seizure before joining the trial
- You must not have taken seizure medication before the trial starts
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving levetiracetam (a seizure-preventing medicine) before and after surgery to remove a brain tumor can reduce the chance of having seizures. It may help patients who have never had a seizure before.
This study tests whether early brain stimulation can help recovery after a moderate to severe traumatic brain injury (TBI). It might help improve thinking and awareness in patients who can already speak and follow directions.
This trial tests two medicines, levetiracetam and lacosamide, to see which works better at preventing seizures in people who have had a traumatic brain injury. The goal is to find the safest and most effective way to protect your brain after injury.
This study tests whether giving an anti-seizure medicine soon after a traumatic brain injury can prevent seizures. It may help people who arrive at the hospital within 24 hours of their injury.
This study looks at two medicines (phenytoin and levetiracetam) to see which works better for treating or preventing seizures that can happen after a traumatic brain injury. It aims to find the safest and most effective option for patients.
This trial tests whether biperiden can lower the chance of developing epilepsy after an acute traumatic brain injury (with bleeding or bruising seen on CT). If you qualify, you would get the medicine or a placebo soon after the injury, and researchers will compare outcomes.
Hear when a new Seizures trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.