Statin therapy to protect the brain during aortic valve replacement
Part of Heart & circulation clinical trials.
This trial tests whether giving a strong dose of a statin (a cholesterol-lowering drug) before and after your TAVR procedure can help protect your brain from damage. It may reduce the risk of thinking or memory problems after the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 65 and 80 years old.
- You have severe narrowing of the aortic valve (aortic stenosis) and are planned to have a TAVR procedure.
- You have normal to moderately healthy overall health (classified as ASA I-III).
- You have not taken cholesterol-lowering statin medications in the past month.
- You have not had a disabling stroke, have good kidney function, and are not allergic to atorvastatin.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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