Intensive statin therapy to protect the brain during TAVR
Part of Heart & circulation clinical trials.
This trial tests whether giving a high dose of a statin (atorvastatin) before and during a heart valve replacement procedure (TAVR) can reduce the risk of brain injury. Statins are cholesterol-lowering drugs that may also protect the brain, and this study aims to see if they help people undergoing TAVR.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 65 and 80 years old.
- You have severe narrowing of your aortic heart valve (aortic stenosis) and are scheduled for a TAVR procedure.
- You have not taken any statin medication in the past month.
- You have no major memory or thinking problems (Montreal Cognitive Assessment score above 20).
- You can have an MRI scan and do not have a permanent pacemaker or severe claustrophobia.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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