Clin2
NCT07206849Possibly a fitNot yet recruiting

Tovorafenib for high-grade glioma and DIPG

High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine GliomaHigh Grade GliomaWHO Grade 3 GliomaWHO Grade 4 GliomaMetastatic Brain Tumor

Treatments studied

Part of Brain & nervous system, Cancer clinical trials.

This trial tests a drug called tovorafenib for children and young adults with certain types of brain tumors that have specific genetic changes. It is aimed at helping people who have just finished radiation therapy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
79 people
Ages
1 year to 39 years
Study type
Interventional

Who can take part

  • You must be between 1 and 39 years old.
  • You must have a high-grade glioma or DIPG with a MAPK pathway alteration.
  • You must have been on the TarGeT-SCR study before.
  • You must start treatment within 35 days after finishing radiation therapy.
  • You need adequate organ function (bone marrow, kidney, liver, heart, thyroid).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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