Metformin for recurrent PFA ependymoma
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests if metformin can help treat a certain type of brain tumor called PFA ependymoma that has come back after surgery and radiation. It's for people ages 1 to 39 who are healthy enough for surgery or have tumors that can be measured on scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your brain tumor must be a specific type (PFA ependymoma) and has come back after you had surgery and radiation.
- You must be between 1 and 39 years old.
- You can either have surgery to remove part or all of the tumor, or have tumors that can be measured on an MRI (at least 1 centimeter across).
- You cannot have diabetes or prediabetes (based on blood sugar tests).
- You cannot have taken metformin before for this tumor, and you must stop other cancer treatments for a few weeks before starting.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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