Exercise and medicine for heart health in ALL survivors with obesity
Treatments studied
Part of Blood & lymphatic, Cancer, Hormones & metabolism, Immune system & allergy clinical trials.
This trial tests if combining resistance exercise with the weight-loss medication tirzepatide can improve heart and metabolic health in survivors of childhood acute lymphoblastic leukemia (ALL) who are now adults and have obesity or overweight with related health issues. You may benefit if you finished treatment at least 2 years ago and meet weight and health criteria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You survived acute lymphoblastic leukemia (ALL) and it has been at least 5 years since your diagnosis
- You completed chemotherapy at least 2 years ago
- You have obesity (BMI over 30) or are overweight (BMI over 27) with a weight-related condition like high blood pressure, high cholesterol, sleep apnea, or heart disease
- You are not currently taking weight-loss medication or have not used any in the past 3 months
- You are willing and able to do resistance exercise and self-inject the study drug
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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