Morphine clearance study for sickle cell crisis in ICU
Part of Blood & lymphatic, Genetic & congenital, Lungs & breathing clinical trials.
This study looks at how the body clears morphine in adults with sickle cell disease who are in the intensive care unit (ICU) for a pain crisis or acute chest syndrome and are receiving morphine through a patient-controlled analgesia (PCA) pump. The goal is to understand how kidney function affects morphine breakdown.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have sickle cell disease (types SS, SC, S-beta+, or S-beta0)
- You are currently in an intensive care unit
- You are having a painful crisis (vaso-occlusive crisis) or acute chest syndrome
- You are receiving morphine through a PCA pump for pain control
- You agree to take part in the study, or a family member can consent for you if you are unable
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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