Testing Isturisa for mild cortisol excess from adrenal tumors
Treatments studied
Part of Cancer, Genetic & congenital, Heart & circulation, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether a drug called Isturisa (osilodrostat) can safely lower mild cortisol excess in people with adrenal tumors. It aims to help patients avoid the long-term effects of too much cortisol.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have mild cortisol excess (MACS) from an adrenal mass seen on a CT or MRI scan
- You have not been treated for Cushing's syndrome or taken strong steroid drugs in the last 3 months
- You don't have severe liver or kidney failure
- You are not pregnant or breastfeeding
- You can have a DEXA scan (bone density test) and agree to study procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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