A study on osilodrostat for high blood pressure caused by Cushing's syndrome
Treatments studied
Part of Cancer, Heart & circulation, Hormones & metabolism clinical trials.
This trial tests whether osilodrostat can lower blood pressure in people with Cushing's syndrome whose high blood pressure is not well controlled by their current medications. The drug works by reducing the production of the stress hormone cortisol, which is abnormally high in Cushing's syndrome.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with Cushing's syndrome (endogenous type).
- Your blood pressure is not well controlled (average daytime reading at least 135/85 mmHg) despite taking blood pressure medications.
- You have not taken any medications for Cushing's syndrome recently (specific washout periods apply).
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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