Metformin for preventing scarring after spinal cord injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma clinical trials.
This trial tests whether the drug metformin can reduce scarring (gliosis) in the spinal cord after a recent thoraco-lumbar injury. If you've had a spinal cord injury in the past 24 hours and meet the criteria, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You had a spinal cord injury between the T1 vertebra and the conus medullaris (the lower end of the spinal cord) in the last 24 hours.
- You have new weakness or numbness from the injury (ASIA grade B, C, or D).
- You can have an MRI of your spine.
- You do not have diabetes, and you are not already taking metformin.
- You do not have other serious conditions like severe brain injury, kidney failure, or metal implants.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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