Clinical trials
Dexmedetomidine clinical trials
Below are recruiting dexmedetomidine clinical trials, each written for real people, not researchers. We’re tracking 176 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT06837844Recruiting
Pain relief study for knee replacement surgery
This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.
Kafr ash Shaykh, KafrelsheikhAges 18–75 - NCT07369128RecruitingPhase 4
Comparing two sleep medicines for children having an MRI
This trial tests whether using one sleep medicine (propofol) alone works as well as using it with another medicine (dexmedetomidine) for children getting an MRI. The goal is to find the safest and most effective way to help kids stay still during the scan.
Boston, MassachusettsAges 1–12 - NCT07329933Recruiting
Steroids and sedatives for faster recovery after gallbladder surgery
This trial tests if adding two medicines, dexamethasone and dexmedetomidine, helps the stomach and intestines work better after keyhole gallbladder removal. The goal is to see if the combination can get your digestion back to normal faster.
BanhāAges 18–65 - NCT07308756RecruitingPhase 4
Study on two drugs for better recovery after surgery
This trial tests if giving two medicines, dexmedetomidine and esketamine, during and after surgery can help you feel better and recover more comfortably. It is for adults having general anesthesia for at least one hour who will use a patient-controlled pain pump afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06981494Recruiting
Study of two medicines for relaxing blood pressure during ear and nose surgery
This trial tests if adding a second medicine, ketamine, to dexmedetomidine helps control blood pressure better during ear or nose surgery. It may lead to safer and smoother anesthesia for patients needing controlled low blood pressure.
SohagAges 18–60 - NCT06399185RecruitingPhase 4
Medicines for catheter discomfort after bladder or prostate surgery
This study tests whether two medicines, dexmedetomidine and esketamine, can reduce discomfort from a urinary catheter after bladder or prostate surgery. If you are having this type of surgery and need a catheter, this trial may help find a better way to manage that discomfort.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05821972RecruitingPhase 4
Breathing-mist medicines for cleft palate surgery pain control
This trial tests whether a breathing mist of two medicines (dexmedetomidine plus ketamine) works better than dexmedetomidine alone during cleft palate repair surgery. It may help improve comfort and safety around anesthesia for eligible patients.
AsyutAges 1–4 - NCT07867899Recruiting
Preventing confusion after hip fracture surgery
This study tests whether a medication called dexmedetomidine, given during or after hip fracture surgery, can help prevent confusion (delirium) that sometimes occurs in older patients after surgery. If you are 65 or older and having hip fracture surgery, this treatment might help you recover more clearly.
AarhusAges 65 years+ - NCT07846722Recruiting
Comparing two medicines to reduce pain medicine use after laparoscopic hysterectomy
This study compares two drugs, esmolol and dexmedetomidine, to see which one better reduces the need for strong painkillers after laparoscopic hysterectomy. It may help you manage pain with fewer opioids.
AthensAges 20–70 - NCT07813962Recruiting
Reducing PTSD risk after trauma surgery
This study tests whether a sedative medication (dexmedetomidine) plus a gentle electrical stimulation on the ear can lower the chance of developing post-traumatic stress disorder (PTSD) after emergency surgery for a serious injury. If you qualify, you will receive this treatment during your operation and be checked for PTSD symptoms for one month afterward.
Nantong, JiangsuAges 18–80 - NCT07807020Enrolling by invitationPhase 1/Phase 2
Lower-dose pain medication for knee replacement surgery
This study tests whether a lower dose of a pain medication given through spinal anesthesia can provide good pain relief after knee replacement surgery with fewer side effects. It may help reduce risks like low blood pressure or slow heart rate.
Islamabad, FederalAges 18–60 - NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery
This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.
Tanta, El-GharbiaAges 21–60 - NCT07780760Recruiting
Numbing throat spray to ease pain after tonsil removal in children
This study tests whether a numbing mist sprayed into the throat before surgery can reduce sore throat pain children feel after having their tonsils removed. It compares two numbing medicines to see if one works better than the other.
Al FayyumAges 3–15 - NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT07693621Recruiting
Pain relief medicine added to numbing drug for gallbladder surgery
This trial tests if adding dexmedetomidine or magnesium to a standard numbing medication (bupivacaine) injected into the belly during gallbladder surgery can improve pain control and recovery. It aims to find a better way to manage pain after surgery.
AlexandriaAges 18–60 - NCT07675616Recruiting
Comparing two drugs for numbing the eye before tear-duct surgery
This trial tests whether adding dexmedetomidine or magnesium sulfate to lidocaine makes numbing the eye more effective for tear-duct surgery. The goal is to find which combination provides better pain control during surgery.
CairoAges 18 years+ - NCT07640516Recruiting
Pain Relief Comparison for Amputation Surgery in High-Risk Patients
This study compares two medications (dexmedetomidine and fentanyl) mixed with a numbing agent to see which works better for blocking pain during above-knee amputation surgery in patients with serious heart or lung disease. Both drugs are already used in anesthesia, and this trial tests which combination is safest and most effective for you.
CairoAges 18 years+ - NCT03596424Recruiting
Testing ketamine and dexmedetomidine during lung surgery
This trial studies whether the anesthesia medicines ketamine and dexmedetomidine can improve care during elective lung (video-assisted) surgery. It may help with comfort during and after the operation, depending on how these medicines affect pain and recovery.
Montreal, QuebecAges 18–80 - NCT07611890RecruitingPhase 4
Comparing two medications to reduce heart stress during cardiac surgery
This trial tests whether dexmedetomidine or lignocaine better prevents dangerous heart-rate and blood-pressure changes when a breathing tube is placed during heart surgery. If you're having cardiac surgery and are at high risk for heart complications, this study may help protect your heart during the procedure.
Rawalpindi, Punjab ProvinceAges 18–65 - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+ - NCT07556133Recruiting
Comparing two sedation medicines during cataract surgery
This study tests two sedation medicines (dexmedetomidine and propofol) used to keep patients calm and comfortable during cataract surgery. Researchers want to see which combination works best and is safest for this common procedure.
BeirutAges 18 years+ - NCT05672225Recruiting
Dexmedetomidine IV pain pump during major abdominal surgery
This trial studies a two-part pain pump given through a vein during major laparoscopic abdominal surgery to help control pain with general anesthesia. It may help by improving comfort while also avoiding certain side effects for people who can safely receive the study medicine.
SeoulAges 20 years+ - NCT07506044Recruiting
Dexmedetomidine in epidural for labor pain relief
This trial tests adding dexmedetomidine to the epidural medicine used for pain relief during labor. If you are in early labor with a healthy pregnancy, this could help manage pain more effectively.
Shebeen El KomAges 18–40
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Common questions
- Are there clinical trials for dexmedetomidine?
- Yes. Clin2 currently lists 176 recruiting dexmedetomidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dexmedetomidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dexmedetomidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.