Clin2
NCT07279493Possibly a fitRecruiting

Testing KPCXM18 injection for acute ischemic stroke within 12 hours

Acute Ischemic Stroke

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests an investigational injection called KPCXM18 for people having an acute ischemic stroke. It is given within 12 hours of symptom onset, in addition to standard clot-dissolving treatment, to see if it improves recovery and safety.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
300 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old.
  • Your stroke symptoms must have started less than 12 hours ago.
  • You must be eligible for or have received standard clot-dissolving treatment (intravenous thrombolysis).
  • A brain scan must show no bleeding or need for a catheter-based clot removal.
  • Your stroke must be moderate to severe (NIHSS score 6 to 24) with some weakness in an arm or leg.
  • You cannot have taken certain other stroke medications (like edaravone or butylphthalide) after this stroke started.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07205328Recruiting· Phase 2
Testing MT200605 for acute ischemic stroke

This trial tests whether MT200605 can help people who recently had an ischemic stroke (a type of stroke caused by a blocked blood vessel). The drug is given within 24 hours of symptoms starting, and you may join even if you received clot-busting treatment already.

Beijing, Beijing Municipality
NCT07047326Recruiting
Urokinase for acute ischemic stroke within 6 hours

This trial tests whether the clot-busting drug urokinase can help people who have had an ischemic stroke (a stroke caused by a blood clot). The goal is to dissolve the clot and improve recovery, as long as treatment starts within 6 hours of the first symptoms.

Beijing, Beijing Municipality
NCT07396337Recruiting· Phase 2
Study of QHRD106 injection for acute ischemic stroke

This trial tests an investigational drug, QHRD106, given as an injection for people who have had a moderate-to-severe acute ischemic stroke. It aims to see if the drug can help recovery when given within 24 hours after the stroke starts, and it is for patients who are not receiving standard clot-busting treatment.

Nanjing, Jiangsu
NCT06137300Not yet recruiting
Study of a new drug for acute stroke from narrowed brain arteries

This trial tests whether a drug called urinary kallidinogenase can help people who have had a stroke caused by a blocked artery in the brain. The drug is given within 48 hours of the stroke, and the study hopes to see if it improves recovery and reduces disability.

Changchun, Jilin
NCT07606807Recruiting· Phase 3
New clot-busting medication for stroke in the extended time window

This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.

Guangzhou
NCT07475949Recruiting· Phase 3
Stroke treatment for unknown wake-up time

This trial tests a clot-busting drug for people who had a stroke but don't know when it started, like waking up with symptoms. It may help reduce disability if given soon after noticing symptoms.

Xiamen, Fujian

Hear when a new Acute Ischemic Stroke trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.