Study of rifampin combo therapy for staph joint infections
Treatments studied
Part of Bones, joints & muscles, Infections clinical trials.
This study tests whether adding rifampin to standard antibiotics works better for people with a staph infection in a joint replacement. It aims to find a more effective treatment for this type of infection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a staph infection in a joint replacement (like a hip or knee replacement).
- You are under 80 years old and generally healthy.
- You do not have a weak immune system or serious liver or kidney problems.
- You are willing to take the study treatment and attend all follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how antibiotic treatment (especially the course length and approach) relates to infection control and results after a two-step surgery for joint infections. If you’ve had a spacer placed, finished at least 6 weeks of antibiotics, and then had the second surgery, the research team may want to follow your outcomes over time.
This trial tests a way to prevent infections for people getting a hip or knee replacement. It compares different methods to see which works best and may help lower your risk of infection after surgery.
This trial tests whether a strong antibiotic called daptomycin, given before surgery, can prevent infection when you get a new joint put in after treating a joint infection. It's for people whose infection was caused by hard-to-treat bacteria like MRSA.
This study tests whether adding the antibiotic rifampicin to standard treatment works better than standard treatment alone for staph infections in hip or knee replacements. The goal is to find a more effective way to clear the infection and avoid more surgeries.
This study looks at how the antibiotic rifampin behaves in the body when used to treat staph infections in bones or joints. It may help doctors better dose the drug for future patients.
This Phase 3 trial compares two antibiotics—rifabutin and rifampicin—for treating staphylococcal (staph) infections around hip or knee joint implants when the implant is kept in place after cleaning (DAIR). It aims to see which drug works better to stop the infection from coming back.
Hear when a new Periprosthetic Joint Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.