Esketamine for better sleep after surgery in postmenopausal women
Treatments studied
Part of Hormones & metabolism, Mental health clinical trials.
This trial tests if a low dose of esketamine, given during anesthesia, can improve sleep quality after lower-limb fracture surgery in postmenopausal women. It aims to find a safe way to help you rest better after your operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman who has gone through natural menopause (no periods for at least 12 months) and are 45 years or older.
- You are scheduled for lower-limb fracture surgery lasting more than 1 hour under general anesthesia.
- Your body mass index (BMI) is between 18 and 28.
- You do not have any sleep disorder like sleep apnea or restless legs, and you haven't taken medications for sleep or hormones in the past 3 months.
- You have no severe health problems like uncontrolled high blood pressure, heart disease, or liver/kidney issues.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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