Osimertinib plus savolitinib for resistant lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a combination of two targeted drugs (osimertinib and savolitinib) for people with a specific type of advanced non-small cell lung cancer that has stopped responding to standard treatments. It may help patients whose cancer has a low number of MET gene copies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Advanced non-small cell lung cancer that no longer responds to osimertinib, chemo-immunotherapy, or anti-angiogenesis therapy
- At least one tumor that can be measured on scans
- A low number of MET gene copies (below 5) detected by a special test called FISH
- Age 18 or older and able to do most daily activities (ECOG score 0-2)
- No serious heart conditions, uncontrolled infections, or other active cancers requiring treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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