A study to find biomarkers in ALS using tiny brain particles
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial collects blood and spinal fluid samples from people being checked for ALS. The goal is to find clues (biomarkers) in tiny particles from nerve cells that could help doctors better understand and diagnose ALS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have symptoms that make your doctor think you might have ALS.
- You are scheduled for standard tests like nerve tests (EMG), brain MRI, spinal tap, and lung function tests.
- You are able to give written permission (informed consent) to join the study.
- You have health insurance or are part of a social security system.
- You do not have an active infection, cancer, or are pregnant/breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study collects a small skin sample (biopsy) from people with ALS, those who carry an ALS gene mutation but have no symptoms, and healthy volunteers. The sample is used to grow cells in the lab to better understand how ALS develops.
This trial studies the “innate immune system” (your body’s first-line immune response) in people with ALS and in comparison groups. It may help researchers understand what drives ALS and how immune changes could relate to symptoms.
This study builds a blood and spinal fluid (lumbar puncture) sample library from people with ALS, ALS-FTD, or similar neurodegenerative diseases. Your samples help researchers study these conditions, even if you are not receiving a new treatment.
This study uses a comprehensive analysis platform to better understand ALS (and related conditions) and help find ways to “remedy and eliminate” it. If you have ALS or are a healthy control who can safely complete questionnaires and possibly an MRI, you may be able to contribute data that researchers use to improve care.
This study is looking for people with ALS to help doctors understand how certain biological markers (biomarkers) change over time. It involves a lumbar puncture (spinal tap) to collect fluid from your spine and regular check-ups.
This trial uses MRI scans to look for “imaging biomarkers” (scan patterns that may help track ALS). It may help researchers better understand disease changes over time and how ALS progresses.
Hear when a new Amyotrophic Lateral Sclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.