Comparing ways to measure blood thinner levels in children
Part of Genetic & congenital, Heart & circulation clinical trials.
This study tests different ways to measure the level of blood thinner (unfractionated heparin) in children's blood while they are in intensive care after heart surgery. The goal is to find the most accurate method so doctors can give the right dose and keep children safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a child from birth up to 17 years old and weigh at least 3.5 kg (about 7.7 pounds).
- You are in an intensive care unit (resuscitation or cardiac intensive care) for a heart condition.
- You are receiving a blood thinner called unfractionated heparin at a full (curative) dose through a central line (a special IV in a large vein).
- You have both a central arterial and a central venous catheter (special tubes placed in large blood vessels).
- Your parents or legal guardians must give written permission for you to take part.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a faster spinning method to measure how well your blood thinner (anti-Xa) is working when your blood sample is fatty. It may help ensure accurate results for patients on certain anticoagulants.
This trial checks whether blood samples taken from a central line using either a syringe flush or a vacuum tube give the same heparin activity results as blood from a vein in the arm. It is designed for patients in the ICU who are on a steady heparin drip.
This trial tests whether giving a blood thinner before placing a central line (a special IV) helps prevent clots in critically ill children. It could lower the risk of problems from the line.
This study is testing a new device, called Quantra, that checks how well your child's blood clots during surgery. By comparing its results to standard lab tests in healthy children, researchers hope to confirm it is accurate and useful for guiding treatment in kids.
This study looks at whether a blood test measuring a substance called anti-factor Xa activity can help predict dangerous blood clots in critically ill patients. If you join, researchers will follow you to see if the test results can prevent clots.
This study looks at how well blood thinners (anticoagulants) and inflammation markers work in people having heart or blood vessel procedures. It aims to better monitor these treatments to improve patient safety.
Hear when a new Congenital Heart Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.