Acetazolamide for fluid removal in acute heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are in the hospital for acute heart failure and have swelling from extra fluid.
- You are already taking furosemide and an SGLT2 inhibitor (like empagliflozin or dapagliflozin).
- Your doctor says you still have leftover fluid that needs another water pill (diuretic).
- Your systolic blood pressure must be 90 or higher (not too low).
- Your kidney function (GFR) must be 20 or above, and you are not on dialysis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new use of the drug acetazolamide (commonly used for other conditions) to help remove extra fluid and reduce weight in people with heart failure. It might help relieve symptoms like swelling and shortness of breath.
This study looks at how your kidneys handle salt and water when you're treated for acute heart failure in the hospital. Researchers want to understand which patients recover well from fluid buildup and which might need different treatment approaches.
This trial tests if using urine sodium levels to guide diuretic (water pill) dosing during hospital care for worsening heart failure can improve outcomes. The goal is to help doctors adjust treatment more effectively to clear extra fluid from the body.
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
This trial tests different water pill (diuretic) strategies for people hospitalized with acute heart failure and too much fluid. It is designed for patients who may not respond well to standard water pills, to find a more effective way to relieve symptoms.
This trial tests whether taking acetazolamide by mouth can help prevent or improve worsening (decompensation) of heart failure after you needed IV water pills (diuretics). It’s mainly for adults with a recent heart-failure flare and specific heart/lab signs, while carefully excluding certain low blood pressure, kidney issues, and electrolyte or acid–base problems.
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.