Comparing two drugs for knee replacement pain relief

This study compares two types of numbing injections (nerve blocks) to see which provides better pain relief after total knee replacement surgery. If you are 65 or older and having your first knee replacement, you may be able to join.

This study tests whether adding two types of nerve blocks plus two medicines can improve pain relief and recovery after knee replacement surgery. It may help patients have less pain and need fewer opioids.

This study compares two ways to manage pain after knee replacement surgery: a special pain-relief injection called Zynrelef versus a nerve block (adductor canal block). The goal is to find which method provides better pain control and helps you recover with fewer opioids.

This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.

This study compares two ways to manage pain after hip replacement surgery: one uses a spinal injection with morphine, and the other uses a nerve block near the hip. The nerve block may include an extra medicine called dexamethasone to see if it improves pain relief.

This study tests whether a medication called dexmedetomidine, given through an IV during hip replacement surgery, can help reduce pain and inflammation after surgery. It may help you recover more comfortably.