Clin2
NCT07389499Possibly a fitNot yet recruiting

GT719 cell therapy for immune kidney diseases

IgA Nephropathy (IgAN)Membranous NephropathyANCA-associated Vasculitis (AAV)/ANCA-associated Glomerulonephritis (AAGN)Refractory PodocytopathyProliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits

Part of Heart & circulation, Immune system & allergy, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.

This trial tests a universal cell therapy called GT719 that targets CD19 on B cells to treat several immune-mediated kidney diseases, including IgA nephropathy, ANCA vasculitis, membranous nephropathy, and others. It may help people who have not responded well to standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have one of these kidney diseases: IgA nephropathy, ANCA vasculitis, membranous nephropathy, podocytopathy, or PGNMID.
  • Your kidney disease must be considered high risk or not responding to standard treatments.
  • You must have CD19 positive B cells in your blood.
  • You cannot have active infections, certain heart or lung problems, or a history of organ transplant.
  • You must agree to use effective birth control for at least one year after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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