Sodium bicarbonate enema for constipation and toxins in kidney disease
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether a sodium bicarbonate enema (a liquid given through the rectum) can help relieve constipation and reduce certain waste products (uremic toxins) in the blood for people with moderate to advanced chronic kidney disease. It may offer a simple, non-drug way to improve comfort and kidney health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have chronic kidney disease stage 3 or 4 (moderate to severe kidney damage).
- Your kidney function has been stable (not getting worse) for the last 3 months.
- You do not have an active bowel disease such as inflammatory bowel disease, colon cancer, severe hemorrhoids, or anal fissures.
- You have not had recent abdominal or colorectal surgery.
- You are not pregnant or breastfeeding, and you do not have a severe heart condition or an electrolyte imbalance.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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