Study of a bone graft for two-level lower back fusion
Part of Bones, joints & muscles clinical trials.
This trial tests a special material (rhBMP-2) placed inside a cage to help two nearby vertebrae in the lower back fuse together. It is for patients whose disc problems or deformity have not improved after at least 3 months of other treatments, and who have significant pain and limited function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You need to have damage or deformity in your lower spine (L2 to S1) that requires surgery to fuse two levels together.
- You must have symptoms like leg pain, numbness, weakness, or trouble walking due to pinched nerves, confirmed by an MRI or other scan within the past year.
- You should have tried non-surgical treatments (like physical therapy or medications) for at least 3 months without enough relief.
- You must be between 18 and 80 years old and have a preoperative disability score of at least 35% (meaning your back problem significantly limits daily activities).
- You cannot have had prior spine surgery at the levels being treated, except for simple decompression like a discectomy.
- You must be able to stop smoking for at least 12 weeks before the procedure and during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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