Stem cell therapy trial for Huntington's disease
Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.
This trial tests whether human neural stem cells are safe and tolerable for people with Huntington's disease. It involves a neurosurgical procedure to inject the cells into the brain, along with MRI scans and other monitoring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old
- You must have a genetic diagnosis of Huntington's disease
- You must be able to make your own decisions and give written consent
- You must be able to undergo MRI scans, brain surgery, blood draws, and a lumbar puncture
- You cannot be pregnant
- You must not have HIV, hepatitis C, or chronic hepatitis B, and no implanted brain stimulation device
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study uses special brain imaging and memory/thinking tests to find early “markers” that can predict how Huntington’s disease will progress over time. You may qualify as someone with early-stage Huntington’s or as a healthy control, if you meet specific safety and scoring requirements.
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This trial tests a new radioactive tracer called [11C]CHDI-00491009 that may show mutant huntingtin protein in the brain using a PET scan. It aims to find out if the tracer is safe and helps see Huntington's disease changes. If you have early-stage Huntington's or are a healthy volunteer, you may be able to join.
This trial tests an at-home, noninvasive brain stimulation treatment to help with behavioral and cognitive (thinking) symptoms in people with Huntington’s disease. You and a caregiver work together during sessions and questionnaires to see if symptoms improve and stay stable.
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