Virtual twins for personalized care in renal denervation
Part of Heart & circulation, Hormones & metabolism clinical trials.
This pilot study uses a computer model (your 'virtual twin') to personalize treatment for high blood pressure or adrenal gland surgery. It aims to see if this approach can improve outcomes for patients with resistant hypertension or primary aldosteronism.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old.
- You have high blood pressure that is either untreated or treated for less than 6 months, or you have a clinical need for renal denervation (a procedure to calm overactive nerves in the kidneys).
- Your blood pressure readings are above 140/90 mmHg in the doctor's office (or above 135/85 mmHg at home or on a 24-hour monitor).
- You may have primary aldosteronism (a hormonal cause of high blood pressure) and need surgery to remove one adrenal gland.
- You are not pregnant and do not have skin irritation at sites where sensors would be placed (sternum, chest, finger).
- You have no known allergies to ultrasound gel, adhesives, electrodes, or plastics.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a procedure called renal denervation for people with untreated high diastolic blood pressure. The procedure uses a small catheter to interrupt nerve signals around the kidneys, which may help lower blood pressure.
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