Comparing two antibiotic treatments for fever after chemo
Treatments studied
Part of Blood & lymphatic clinical trials.
This trial tests whether a single antibiotic (amoxicillin-clavulanate) works as well as a combination of two antibiotics (amoxicillin-clavulanate plus ciprofloxacin) for treating fever caused by chemotherapy in people with blood cancer. It aims to simplify treatment and reduce antibiotic use while still keeping you safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have a type of blood cancer (like lymphoma, myelodysplasia, or acute myeloid leukemia) and are getting chemotherapy that will likely cause a low white blood cell count for less than a week.
- You have not had a stem cell transplant or CAR-T cell therapy.
- You are not allergic to the antibiotics being tested (amoxicillin-clavulanate or ciprofloxacin).
- You are not pregnant, breastfeeding, or planning to become pregnant, and you use effective birth control.
- You do not have certain medical conditions like long QT syndrome, severe lung disease (COPD), or kidney problems (creatinine clearance below 30).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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