Antibiotics for chemotherapy-related fever in blood cancer patients
Treatments studied
Part of Blood & lymphatic clinical trials.
This trial tests whether a single antibiotic (amoxicillin-clavulanate) works as well as taking two antibiotics (amoxicillin-clavulanate plus ciprofloxacin) for fever caused by chemotherapy in people with certain blood cancers. The goal is to treat the fever at home, avoiding a hospital stay, while keeping you safe and comfortable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and have a blood cancer such as lymphoma, myelodysplastic syndrome, or a type of acute myeloid leukemia that is being treated with a gentler chemotherapy.
- Your doctor expects your white blood cell count to be low (called neutropenia) for less than a week due to chemotherapy.
- You need to be able to understand the study and fill out a simple follow-up form (by phone or on paper).
- You cannot have had a bone marrow transplant, CAR-T cell therapy, or a previous serious fungal infection.
- You must not have certain allergies (like to penicillin or ciprofloxacin) or medical conditions such as epilepsy or kidney problems.
- You must not be pregnant or breastfeeding, and you must use contraception if you can become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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