Brain radiation that tries to protect memory
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a special type of whole-brain radiation that aims to avoid the parts of the brain that control memory. It's for people with many brain tumors (6 or more) that haven't been treated with radiation before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with cancer (not blood cancer) that has spread to your brain.
- You have 6 or more brain tumors that haven't been treated with radiation or surgery yet.
- You are 18 years or older.
- You are generally able to care for yourself (Karnofsky score of 60% or higher).
- Your doctor expects you to live at least 6 more months.
- You don't have cancer in the fluid around your brain (leptomeningeal metastasis) or metal implants that would prevent an MRI.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
This trial compares two types of whole brain radiation for people with many brain tumors. One method tries to protect parts of the brain important for memory, while the other does not. It aims to see which approach helps maintain thinking and memory better.
This Phase 2 study tests a treatment plan that combines whole-brain radiation therapy with an additional approach to help people with brain metastases. It aims to improve outcomes while also tracking brain function and memory over time.
This trial studies a “prophylactic” (preventive) type of brain radiation for people with lung cancer that has spread to nearby lymph nodes but not to the brain. It aims to lower the chance of brain metastases while protecting the hippocampus, an area linked to memory.
This Phase 2 trial tests a modified form of whole brain radiation to see if it can better protect thinking and memory in adults with brain metastases. You may join even if you’ve had other cancer treatments before, as long as your situation fits the study rules.
This trial compares two types of radiation for people with small cell lung cancer that has spread to the brain (10 or fewer spots). One approach uses focused radiation only on the tumors, the other treats the whole brain while trying to protect memory. The goal is to see which works better with fewer side effects.
Hear when a new Brain Metastases From Solid Tumors trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.