Brain radiation that avoids the memory area in lung cancer
Part of Brain & nervous system, Cancer, Lungs & breathing clinical trials.
This trial studies a “prophylactic” (preventive) type of brain radiation for people with lung cancer that has spread to nearby lymph nodes but not to the brain. It aims to lower the chance of brain metastases while protecting the hippocampus, an area linked to memory.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of non-small-cell lung cancer (NSCLC).
- You are 18 or older and have already had definitive lung surgery, with pathology showing lymph node metastasis.
- You have completed or are receiving platinum-based chemotherapy.
- Your health is strong enough for treatment (ECOG better than 2, or Karnofsky score above 70).
- You can speak/read Mandarin well enough to take part in the study.
- You must not have had any prior cranial (brain) radiation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether avoiding the hippocampus (a part of the brain important for memory) during whole-brain radiotherapy can slow down thinking and memory decline. It may help some people preserve neurocognitive function while still treating brain metastases.
This trial tests a new way to deliver radiation to brain metastases from non-small cell lung cancer, using MRI scans to guide the treatment and reduce the area exposed. The goal is to see if this approach is safe and effective while possibly lowering side effects.
This study tests whether focusing high-dose radiation only on brain tumor spots, while avoiding the hippocampus (a brain area important for memory), helps protect memory and thinking compared with standard whole-brain radiation. It’s for people with small cell lung cancer that has spread to the brain.
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
This trial compares two types of radiation for people with small cell lung cancer that has spread to the brain (10 or fewer spots). One approach uses focused radiation only on the tumors, the other treats the whole brain while trying to protect memory. The goal is to see which works better with fewer side effects.
This trial compares two types of whole brain radiation for people with many brain tumors. One method tries to protect parts of the brain important for memory, while the other does not. It aims to see which approach helps maintain thinking and memory better.
Hear when a new Brain Metastasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.