Pemafibrate to prevent stroke from brain artery narrowing
Treatments studied
Part of Brain & nervous system, Heart & circulation, Hormones & metabolism clinical trials.
This trial tests whether a medication called pemafibrate can help prevent future strokes in people who have had a recent stroke or TIA (mini-stroke) caused by a narrowed artery inside the brain. The medication works by lowering triglycerides (a type of fat in the blood).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke or high-risk TIA within the past 3 years and your condition is stable
- A recent CT scan (within 3 months) shows 50–99% narrowing of an artery inside your brain
- Your triglyceride levels are elevated (150–499 mg/dL depending on whether you fasted)
- You are 18 years or older and able to give informed consent
- You have not taken pemafibrate or other fibrate drugs in the past 12 weeks
- You do not have severe liver disease, gallstones, pancreatitis history, or dialysis-dependence
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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