Pacemaker Pacing Strategies for Heart Failure Patients
Part of Heart & circulation clinical trials.
This study tests whether optimized pacemaker settings can improve heart function and symptoms in heart failure patients who need a pacemaker for a slow heartbeat. The goal is to find the best way to program the pacemaker to help your heart work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have symptoms from a slow heartbeat and need a permanent pacemaker
- You have heart failure with a preserved ejection fraction (your heart pumps at least 50% of its blood with each beat)
- You show signs of heart failure through test results (like elevated BNP blood test, hospitalization history, or diuretic use)
- Your pacemaker will be able to pace your heart in a natural way (not just in the lower chamber)
- Your heart rate is slow enough that the pacemaker will do most of the work (not just back you up occasionally)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests how pacing from a specific part of the heart (a “bundle” pacing approach) can affect people with heart failure and/or slow heart rhythms. It may help certain patients whose heart rhythm is too slow or who need a pacemaker and related devices.
This study compares two types of heart pacing—one that mainly targets the heart’s lower chambers versus one that targets the right side—to see which leads to better outcomes for people needing a pacemaker. It may help improve treatment for certain slow heart rhythm problems that require pacing.
This study tests whether a specific pacemaker heart-rate setting helps control blood pressure and improve heart function in adults over 65 with slow heartbeats and high blood pressure. You would receive a dual-chamber pacemaker (a standard treatment) and be monitored to see how the rate setting affects your health.
This trial compares two ways to place a heart pacemaker in patients with an abnormally wide heartbeat pattern. Researchers want to see if a newer pacing technique that targets the heart's natural conduction system works better than traditional pacing methods.
This trial studies whether a strategy to regularize (control) heart rate can improve outcomes in people who have permanent atrial fibrillation and heart failure. It focuses on people with recent heart-failure hospitalization and checks several heart, kidney, and health-condition limits to keep the study safe.
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
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