Dexmedetomidine for septic shock not improving with standard treatment
Treatments studied
Part of Heart & circulation, Infections clinical trials.
This study tests a medicine called dexmedetomidine, which may help calm the body's stress response during septic shock, possibly improving blood pressure and organ function. The trial is for patients in intensive care who are already on strong blood pressure support but are not improving.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have septic shock (a severe infection causing very low blood pressure) that is not improving with standard treatment.
- You need to be on a breathing machine (ventilator) to help you breathe.
- You must be receiving a strong blood pressure medication (norepinephrine) at a high dose for more than 2 hours.
- Your heart rate must be above 55 beats per minute (unless you take a beta-blocker), and you must not have a serious heart block.
- You cannot be pregnant or breastfeeding, and you must not have severe liver failure or other conditions listed in the full criteria.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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