Lowering norepinephrine in shock: effects on blood vessel pressure
Part of Heart & circulation clinical trials.
This study tests whether reducing the dose of a medicine that raises blood pressure (norepinephrine) affects how blood moves through the body in people with distributive shock. If you are on a steady low dose of norepinephrine and have a special heart monitor (PiCCO catheter), this trial may help doctors understand safer ways to wean the medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older with distributive shock
- You are receiving norepinephrine (a blood-pressure-raising medicine) and your mean arterial pressure is between 75 and 85 mmHg
- You have a PiCCO catheter in place (a thin tube that measures blood flow from the heart)
- You are on a breathing machine (mechanical ventilation)
- Your doctor has decided it is safe to try reducing your norepinephrine dose
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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