Clinical trials
Back Pain clinical trials
Below are recruiting back pain clinical trials, each written for real people, not researchers. We’re tracking 393 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05721027RecruitingPhase 4
Ibuprofen alone or with a steroid for new sciatica pain
This trial compares ibuprofen alone versus ibuprofen plus dexamethasone (a steroid) for short-term relief of acute nerve-related low back pain that shoots into the buttock or leg. It aims to see which approach reduces pain and improves function after an emergency visit.
The Bronx, New YorkAges 18–70 - NCT06924671Recruiting
GLA:D Back Canada program for chronic low back pain
This study tests a program called GLA:D Back Canada, which is designed to help people with long-lasting low back pain. It focuses on exercises and education to improve your back health and daily function.
Edmonton, AlbertaAges 18 years+ - NCT07528833Recruiting
Mindfulness stress reduction for chronic back pain
This study tests whether a mindfulness-based stress reduction course can help reduce back pain. Mindfulness teaches you to focus on the present moment and manage stress, which may help ease chronic pain in your lower or mid-back.
TampereAges 18–64 - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT07535047Recruiting
How Placebo and TENS Work Together for Lower Back Pain
This study tests whether the expectation of pain relief (the placebo effect) can make a device called TENS (transcutaneous electrical nerve stimulation) work better for acute lower back pain. TENS uses gentle electrical pulses on your skin to reduce pain.
Giza, Giza GovernorateAges 18–65 - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT07368920Recruiting
TENS for low back pain in adults
This study tests if a non-invasive device called TENS (which uses gentle electrical pulses) can help relieve low back pain that comes from muscle knots or tight bands. The device is applied to the skin over the painful area.
Xi'an, ShaanxiAges 18–65 - NCT07338877Enrolling by invitation
Stem cell therapy for disc-related low back pain
This trial tests a new treatment that uses your own stem cells to help heal damaged discs in your lower back. The stem cells are injected into the disc during a minimally invasive procedure to reduce pain and improve function.
Košice, Košice RegionAges 18 years+ - NCT07339631RecruitingPhase 1
Sodium Aescinate for Chronic Low Back Pain in Adults
This study tests an injectable medication called sodium aescinate (derived from horse chestnut) for people with chronic low back pain. It aims to see if it helps reduce pain and is safe to use.
Xi'an, ShaanxiAges 18–65 - NCT07284407Recruiting
Learning about pain and touch training for long-term back pain
This study tests two types of therapy for ongoing low back pain: learning about how pain works (pain education) and training your sense of touch (sensory discrimination). The goal is to help your brain process pain better and reduce discomfort.
LahoreAges 19–44 - NCT07251959Enrolling by invitation
Exercise vs. exercise plus manual therapy for chronic back pain
This study tests whether a workplace exercise program, with or without hands-on manual therapy, can help reduce chronic spinal pain in desk workers. It is designed for UCAM University staff who have had persistent back pain for at least 3 months.
Murcia, MurciaAges 18 years+ - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65 - NCT07190807Recruiting
Optimizing spinal cord stimulation for chronic back and leg pain
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
Greenwood, ColoradoAges 18 years+ - NCT07176845Recruiting
Tracking back pain patterns with your smartphone
This study uses your smartphone's motion sensors to track how your back pain changes over time. It might help you understand your pain patterns — and helps researchers learn more about low back pain.
BernAges 18 years+ - NCT07178561Recruiting
Exercise for older adults with chronic back pain and anxiety
This study tests whether a supervised exercise program can reduce disability and improve mental health in older adults with chronic low back pain, poor sleep, and mild to moderate anxiety or depression.
Gaza, Gaza StripAges 55–70 - NCT07161661Recruiting
Osteopathic treatment for chronic low back pain in veterans
This trial tests whether adding osteopathic manipulative treatment (OMT) to standard VA care helps reduce chronic low back pain. OMT involves a healthcare provider using their hands to move and stretch muscles and joints.
Hines, IllinoisAges 18 years+ - NCT07150702Recruiting
Close follow-up for low back pain
This study is testing whether closer follow-up care helps people with long-term low back pain feel better faster. You'll receive a standard physical therapy program but with more frequent check-ins to see if extra support improves your recovery.
Istanbul, FatihAges 18–65 - NCT07137065Recruiting
A new approach to managing low back pain in primary care
This study tests a program designed to help people with low back pain get better care from their general practitioner. If you have low back pain (with or without leg pain) and haven't seen your doctor for this same problem in the last 3 months, you may be able to join.
Geneva, Canton of GenevaAges 18 years+ - NCT07137715Recruiting
Wellness and recovery for veterans with chronic back or neck pain
This study tests a psychological program to help veterans manage chronic back or neck pain. It aims to improve your wellbeing and daily function through counseling or coaching sessions.
Aurora, ColoradoAges 18 years+ - NCT07112404Recruiting
Dry Needling for Low Back Pain Study
This study tests a type of dry needling (inserting thin needles into muscles) to see if it helps people with and without chronic low back pain. You may join if you have no recent low back pain or if you have had low back pain for at least 3 months, as long as you have not had major back surgery or certain treatments.
Galveston, TexasAges 18–65 - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT06987175Recruiting
Sedante Neo therapy for low back pain
This study tests a therapy called Sedante Neo to see if it reduces pain, improves movement, and boosts quality of life in people with common low back pain. It is designed for adults aged 20–40 whose back pain is mild to moderate and affects daily life.
Lahore, Punjab ProvinceAges 5 months–9 months - NCT06984354Recruiting
Digital treatments for chronic low back pain
This trial tests a smartphone app to help people with long-term low back pain. It aims to see if digital treatments can reduce pain and improve daily function.
Randwick, New South WalesAges 18 years+
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Back Pain trials by city
Studies with a site in or near these metro areas.
Back Pain trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for back pain?
- Yes. Clin2 currently lists 393 recruiting back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.