Clin2
NCT07690618Possibly a fitRecruiting

Heat therapy for head and neck cancer

Head and Neck CancerOropharyngeal CarcinomaHypopharyngeal CarcinomaLaryngeal CarcinomaHead and Neck Squamous Cell CarcinomaOral Cavity CarcinomaLocally Advanced Head and Neck Carcinoma

Part of Cancer, Ear, nose & throat, Injuries & trauma, Lungs & breathing, Mouth & dental clinical trials.

This phase 1 trial tests adding heat therapy (thermotherapy) to standard radiation (with or without chemo) for head and neck cancer. It aims to see if it is safe and effective for patients with locally advanced disease who have not had radiation before.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • You can open your mouth at least 40 mm (women) or 45 mm (men).
  • You have a type of head and neck cancer called squamous cell carcinoma (diagnosed by a biopsy).
  • Your cancer is locally advanced (stage III or IV) and you are getting radiation (with or without chemo) as a first-time treatment.
  • You have not had radiation to the same area before.
  • You are willing and able to follow the study schedule and give written consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06659146Recruiting
Heat therapy with standard palliative radiation for cancer

This trial tests whether adding heat therapy (using a special lamp) to standard palliative radiation can help treat superficial tumors or lymph nodes that cannot be cured. It aims to improve symptom relief or tumor control for people with advanced cancer.

London
NCT05526924Recruiting· Phase 1
Phase 1 trial tests re-radiation plus immunotherapy and a cancer pill

This trial studies whether adding a checkpoint immunotherapy (tislelizumab) and a cancer pill (pamiparib) to radiation can better treat cancer that has come back in the head and neck. It’s for adults with previously treated, HPV-positive oropharynx tumors, usually without widespread spread.

Chicago, Illinois
NCT05674396Recruiting· Phase 2
Short-course radiation to ease symptoms from head and neck cancer

This Phase 2 trial tests a specific, shorter type of focused radiation to help relieve symptoms from head and neck squamous cell carcinoma. It compares two radiation timing/planning approaches to see which better improves comfort and quality of life.

Houston, Texas
NCT06248996Recruiting· Phase 3
Testing a stronger radiation schedule for large head and neck cancers

This trial tests whether giving a slightly different schedule of radiation (more frequent, smaller doses) can improve treatment for people with large head and neck cancers. It is for patients who are getting radiation as their main treatment, sometimes with chemotherapy as well.

Gävle
NCT07209189Recruiting· Phase 2
Chemo and immunotherapy before surgery for head and neck cancer

This trial tests a combination of chemotherapy and an immunotherapy drug called Toripalimab before surgery for certain head and neck cancers. The goal is to see if this approach can reduce the extent of treatment needed while still being effective.

Baltimore, Maryland
NCT07253402Recruiting
Microbiota-guided radiation therapy for head and neck cancer

This trial is testing a new way to use radiation therapy for head and neck cancer by also looking at the bacteria in your mouth and gut. The goal is to see if adjusting the treatment based on your bacteria can improve outcomes and reduce side effects.

Milan, Milan

Hear when a new Head and Neck Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.