Clinical trials
ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION clinical trials
Below are recruiting atrial appendage closure for atrial fibrillation clinical trials, each written for real people, not researchers. We’re tracking 74 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07262255Recruiting
Watchman FLX Pro heart device study in Europe
This study tracks people with atrial fibrillation (an irregular heartbeat) who get the WATCHMAN FLX Pro device to reduce stroke risk. It collects real-world data on how well the device works and how safe it is.
AarhusAges 18 years+ - NCT07575269Recruiting
New ablation treatment for irregular heartbeat
This trial tests a new tool called FARAFLEX that uses pulsed electrical energy to treat atrial fibrillation (an irregular heart rhythm). The goal is to see if this method can safely stop AF symptoms in people whose medications haven't worked.
Jonesboro, ArkansasAges 18 years+ - NCT05204212Recruiting
Heart procedure to close an atrial clot risk pouch in kidney failure
This trial tests a heart procedure that closes a part of the heart called the left atrial appendage to help prevent stroke in people with an irregular heartbeat (atrial fibrillation) and very advanced kidney disease. It’s mainly for patients who can take the needed blood-thinner medicines and who do not already have a clot in that pouch.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT07125417RecruitingPhase 4
Blood thinner comparison after left atrial appendage closure
This study compares two approaches after a left atrial appendage closure (LAAC) procedure: taking no blood thinner versus taking just one antiplatelet medication. It aims to see which option is safer for people with atrial fibrillation who are at risk for bleeding.
Nagoya, Aichi-kenAges Any age - NCT06060912Recruiting
Comparing two heart devices to prevent stroke in atrial fibrillation
This study compares two devices (LAmbre and AMPLATZER Amulet) that are placed in the heart to prevent strokes in people with atrial fibrillation who cannot take blood thinners. If you join, you will be randomly assigned to get one of the two devices.
Munich, BavariaAges 18–100 - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT06348394Recruiting
Comparing heart imaging methods for a procedure to prevent stroke
This trial is testing two ways to guide a procedure that closes a small pouch in the heart to lower the risk of stroke in people with atrial fibrillation. The goal is to see if one method is as good or better than the other.
Plano, TexasAges 18–90 - NCT07453940Enrolling by invitation
Closing off heart pouch with or without pulsed energy in atrial fibrillation
This study tests if adding a special energy treatment (pulsed field ablation) to a standard heart pouch closure is safe and works better for people with persistent atrial fibrillation who have few symptoms but a high risk of stroke.
Hangzhou, ZhejiangAges 18 years+ - NCT07349121Recruiting
Testing the Farapulse and Watchman devices together
This trial is for people who need both a special heart treatment called pulsed field ablation (FARAPULSE) and a device to close off a small pouch in the heart (WATCHMAN FLX Pro or WATCHMAN FLX) to prevent strokes. The study will see how well both procedures work when done together.
AalstAges 18 years+ - NCT03409159Recruiting
Left atrial appendage closure registry in Austria
This study keeps records of people who already had a procedure to close a part of the heart called the left atrial appendage in Austria. It helps doctors understand outcomes and safety for patients after the procedure.
GrazAges 18 years+ - NCT03445949RecruitingPhase 4
Best blood-thinner plan after a left heart device procedure
This trial compares which two medicines work best after a device closes off a part of the heart called the left atrial appendage. It may help reduce stroke risk while balancing bleeding risk after your procedure.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT04796714RecruitingPhase 4
Aspirin and clopidogrel after left heart appendix closure
This trial studies a “double anti-platelet” medicine plan (aspirin plus clopidogrel) after closing the left atrial appendage, a procedure used to reduce stroke risk in some heart rhythm conditions. It aims to find a safer, better medicine strategy for people who cannot take standard blood thinners.
PessacAges 18 years+ - NCT04800913Recruiting
Imaging tests during left atrial appendage closure
This study looks at how different imaging tests can help guide a procedure that closes off the left atrial appendage to reduce stroke risk. It may help doctors choose the safest approach during the procedure.
BudapestAges 18 years+ - NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT05144503Recruiting
Test of a new catheter procedure for irregular heart rhythm
This study checks how safe and effective a special catheter procedure (SpherePVI) is for treating paroxysmal (comes and goes) or persistent atrial fibrillation. You may be considered if your atrial fibrillation keeps returning and you’ve already tried at least one medication but it didn’t work or you couldn’t tolerate it.
VilniusAges 18–75 - NCT05164107Recruiting
Test a new pulsed-field catheter procedure for atrial fibrillation
This trial tests a new pulsed-field device used during an atrial fibrillation (AF) catheter ablation, aiming to improve safety and effectiveness. It’s for people who have AF and are planning an AF ablation procedure.
PragueAges 18–75 - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT05565209Recruiting
Registry for closing the left atrial appendage
This study is a hospital registry that collects information from people who are having a device placed to close a part of the heart called the left atrial appendage. It helps doctors understand how this procedure works in real life, including different outcomes.
CréteilAges 18 years+ - NCT05660811RecruitingPhase 4
Antiplatelet medicines after left atrial closure in dialysis patients
This trial looks at the best blood-thinning (antiplatelet) plan after a left atrial appendage closure procedure in people with kidney failure on dialysis. It may help reduce stroke risk while also lowering medicine-related side effects.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT05951101Recruiting
Device to close an irregular heartbeat heart pocket safely
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
Parkville, VictoriaAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for atrial appendage closure for atrial fibrillation?
- Yes. Clin2 currently lists 74 recruiting atrial appendage closure for atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial appendage closure for atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial appendage closure for atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.