Ultrasound guidance for leg artery procedures in critical limb ischemia
Part of Heart & circulation clinical trials.
This trial tests whether using a special ultrasound probe inside the arteries (called IVUS) during a procedure to open blocked vessels below the knee can improve outcomes for patients with critical limb ischemia — a serious lack of blood flow that causes pain, sores, or gangrene. If you qualify, the procedure may help heal your wounds and relieve pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have critical limb ischemia, which means you have severe pain in your foot or leg at rest, or non-healing sores or gangrene, due to poor blood flow
- Have had imaging (like CT, MRI, or ultrasound) in the past year showing blocked arteries below the knee
- Have certain low blood pressure measurements in your ankle or toe (from a test called ABI or TBI)
- Have open arteries from your aorta down to just above the knee — either naturally or from a prior procedure — or be able to have them opened successfully during the same procedure
- Be able to take blood-thinning medicines and not have a condition that causes easy bleeding
- Have no recent major heart attack or stroke, severe liver disease, advanced kidney failure, or life expectancy of less than a year
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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