Detecting heart amyloidosis with pacemaker signals
Part of Brain & nervous system, Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.
This study uses signals from a pacemaker or defibrillator to help detect a condition called cardiac amyloidosis, where abnormal proteins build up in the heart. It may help diagnose this condition earlier without extra tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older.
- You are getting a pacemaker or defibrillator because of a slow or irregular heartbeat.
- Your heart muscle is thicker than normal (a condition called left ventricular hypertrophy).
- You do not have severe narrowing of a heart valve (aortic stenosis).
- You have not been diagnosed with cardiac amyloidosis before.
- Your heart's pumping function is not severely reduced (ejection fraction is 45% or higher).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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