Clin2
NCT07780292Possibly a fitNot yet recruiting

Low-dose azithromycin after sinus surgery for nasal polyps

Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Treatments studied

Part of Immune system & allergy, Infections, Lungs & breathing clinical trials.

This study tests whether taking a low dose of an antibiotic called azithromycin after sinus surgery helps reduce nasal polyps and improve symptoms. It is for adults with chronic sinusitis and nasal polyps who are not allergic to this type of medicine.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
52 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have a confirmed diagnosis of chronic sinusitis with nasal polyps (long-term sinus inflammation with growths in your nose).
  • Your nasal polyps should be on both sides (not just one side) and not caused by fungus, tumors, or other specific conditions.
  • You should have moderate to severe symptoms, as measured by standard scoring tools.
  • You must be able to attend follow-up visits as scheduled and agree to the study's consent process.
  • You should not have significant heart, liver, or kidney problems, serious allergies to macrolide antibiotics, or be pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07200336Not yet recruiting· Phase 4
Medicine plus simple polyp removal versus extended sinus surgery

This study compares two ways to treat chronic sinusitis with nasal polyps: giving a medicine that targets a specific type of inflammation (anti-IL-5 therapy) along with simple removal of polyps, versus a more extensive sinus surgery. The goal is to see which approach better controls your symptoms and reduces the need for repeat treatment.

Chongqing, Chongqing Municipality
NCT06231004Not yet recruiting
Nasal microbiome in chronic sinusitis with nasal polyps

This study looks at how bacteria in the nose relate to a type of chronic sinusitis with nasal polyps. It may help find better treatments for this condition.

NCT07616609Not yet recruiting
New medicine before sinus surgery for nasal polyps

This study tests a new medication (stapokibart) given before sinus surgery to reduce inflammation from nasal polyps. It may improve surgical results and long-term symptom relief.

Beijing, Beijing Municipality
NCT07795658Not yet recruiting
Nasal polyps registry for long-term tracking

This study collects information from people with chronic rhinosinusitis and nasal polyps in both nostrils. By tracking patients over time, researchers hope to learn more about the condition and how to improve care.

Beijing, Beijing Municipality
NCT07755371Not yet recruiting· Phase 2
Testing AK139 for nasal polyps and chronic sinusitis

This study tests a new medicine called AK139 (given as an injection) to reduce nasal polyps and improve breathing. It is for adults with chronic sinusitis and nasal polyps who still have symptoms despite using steroid sprays.

Shanghai
NCT07107256Recruiting· Phase 3
Study of TQC2731 for chronic sinusitis with nasal polyps

This trial tests an injectable drug called TQC2731 for people with chronic sinusitis and nasal polyps that haven't been controlled well enough by standard treatments like steroid sprays or surgery. The goal is to see if it helps reduce nasal congestion, improve sense of smell, and shrink polyps.

Fuyang, Anhui

Hear when a new Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.