Brain stimulation for loss of pleasure in depression
Part of Brain & nervous system, Mental health clinical trials.
This study tests a type of brain stimulation called iTBS (repetitive magnetic pulses) to see if it can help people with depression who feel little pleasure in life. The treatment targets a brain area involved in reward, and may improve your mood and ability to enjoy things.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 45 years old and right-handed
- You have a diagnosis of major depression (confirmed by at least two doctors)
- You score at least 20 on the depression scale (MADRS) or 17 on the HAMD-17
- You have significant loss of interest or pleasure (anhedonia), measured by a questionnaire
- Your antidepressant medication has been the same dose for at least 4 weeks before the study starts
- You do not have a history of seizures, brain injury, or metal implants in your head
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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