Stem cells plus bypass surgery for chronic heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether injecting stem cells from umbilical cord tissue into the heart muscle during bypass surgery can improve heart function in people with chronic heart failure. It is for patients who are already scheduled for bypass surgery and have a weakened heart pump (LVEF between 21% and 40%).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have long-term heart failure caused by blocked arteries (ischemic cardiomyopathy).
- Your heart's pumping ability (LVEF) is between 21% and 40%.
- You have heart failure symptoms, even with mild activity (NYHA class II–IV).
- You are planning to have bypass surgery (CABG) to improve blood flow to your heart.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
This trial tests a new treatment using heart muscle cells made from stem cells (iPSC-CMs) combined with either a heart pump (LVAD) or bypass surgery (CABG) for people with end-stage heart failure. The goal is to see if adding these cells can help the heart work better.
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
This trial tests whether injecting special cells (HiCM-188) during bypass surgery can help improve heart function in people with advanced heart failure. The cells may help repair damaged heart tissue and improve your heart's ability to pump blood.
This trial tests if umbilical cord stem cells, given alongside standard care, can help people who have had a major heart attack (STEMI). The cells are infused into the heart artery to possibly improve heart function. You may qualify if you are between 20 and 76, had a heart attack within the last 12 hours, and received a stent, and your heart's pumping ability is moderately reduced.
This study tests an experimental drug (ADR-002K) for people with heart failure caused by blocked arteries who are about to have bypass surgery. The goal is to see if it helps the heart recover better after surgery.
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