Stem cells plus bypass surgery for chronic heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether injecting stem cells from umbilical cord tissue into the heart muscle during bypass surgery can improve heart function in people with chronic heart failure. It is for patients who are already scheduled for bypass surgery and have a weakened heart pump (LVEF between 21% and 40%).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have long-term heart failure caused by blocked arteries (ischemic cardiomyopathy).
- Your heart's pumping ability (LVEF) is between 21% and 40%.
- You have heart failure symptoms, even with mild activity (NYHA class II–IV).
- You are planning to have bypass surgery (CABG) to improve blood flow to your heart.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new treatment using donor stem cells injected into the heart during scheduled bypass surgery. The goal is to see if these cells help improve heart function in people with heart failure due to blocked arteries and a weak heart pump.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
This trial tests whether injecting special heart muscle cells (made from stem cells) during a heart bypass or a heart pump surgery can help improve your heart's function. It is for people with severe heart failure who are already planning one of these surgeries.
This trial tests whether placing a special membrane with stem cells on the heart during bypass surgery can help improve heart function in people with a weak heart after a previous heart attack.
This trial tests a patch made from lab-grown heart cells that is placed on the heart during bypass surgery. It aims to improve heart function in people with very advanced heart failure who are already having bypass surgery.
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