Clinical trials
Acetaminophen clinical trials
Below are recruiting acetaminophen clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT07710729RecruitingPhase 1
How UBT251 Affects Birth Control and Stomach Emptying
This study tests a new medicine, UBT251, to see if it affects how birth control pills work and how quickly food leaves the stomach. It is for women with overweight or obesity who cannot get pregnant.
Montreal, QuebecAges 18–65 - NCT07661459RecruitingPhase 2
Antihistamine and aspirin with immunotherapy for solid tumors
This trial tests whether taking a daily antihistamine (like Claritin) and a daily aspirin alongside your immunotherapy can make the treatment work better. It's for people with solid tumors who are about to start a PD-1 or PD-L1 blocker.
Lexington, KentuckyAges 18–99 - NCT07632274RecruitingPhase 1
Testing a pain reliever liquid for children ages 6–11
This study tests a new liquid medicine that combines ibuprofen and acetaminophen (two common over-the-counter pain relievers) in children aged 6 to 11. Researchers want to see how well the medicine works and how safe it is for mild to moderate pain, such as headaches, toothaches, or pain after dental work or vaccines.
Salt Lake City, UtahAges 6–11 - NCT07570173RecruitingPhase 2/Phase 3
MK-1045 for Hard-to-Treat B-Cell Leukemia
This trial tests a new drug called MK-1045 in patients whose acute lymphoblastic leukemia (a blood cancer) has come back or stopped responding to previous treatments. The goal is to see if this drug can help control the cancer when other options haven't worked.
Toronto, OntarioAges 12 years+ - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT07571252RecruitingPhase 4
Pain Relief Before Jaw Surgery: A Study
This study tests whether taking pain medicine before jaw surgery (orthognathic surgery) helps reduce pain after the procedure. If you're having jaw surgery, this trial may help doctors understand the best way to manage your pain.
San JuanAges 21–65 - NCT07466108Recruiting
IV paracetamol during emergency abdominal surgery
This trial tests whether giving paracetamol (Tylenol) through a vein during emergency belly surgery helps keep your blood pressure and heart rate stable. It may be an option for adults who are not critically unstable or have certain serious heart conditions.
Cairo, Cairo GovernorateAges 21–65 - NCT07440069RecruitingPhase 4
Pain relief options for women during active labor
This trial compares the pain relief and effects of tramadol, paracetamol (also known as acetaminophen), and a placebo in women during active labor. It aims to find which option works best and is safest for mothers and babies.
Tegucigalpa, Francisco Morazán DepartmentAges 15–45 - NCT07393503Enrolling by invitationPhase 4
Pain relief for new muscle and joint injuries
This trial compares two common treatments for new muscle or joint pain: an over-the-counter pain reliever (Tylenol and ibuprofen) versus an oral steroid (a stronger anti-inflammatory medication). The goal is to see which option works better for short-term pain and recovery.
Buffalo, New YorkAges 18 years+ - NCT04964310Recruiting
Testing genetic risk for acetaminophen-related liver injury
This study looks at whether certain genes can predict who is more likely to get liver injury after taking acetaminophen (also found in some cold/flu medicines). By comparing people who were affected with people who were not, it may help doctors identify higher-risk patients in the future.
Nanjing, JiangsuAges 14 years+ - NCT07337902Recruiting
Comparing pain medicines for menstrual cramps in Crohn’s disease
This study tests two common over-the-counter pain relievers (ibuprofen and acetaminophen) to see which works better for menstrual cramps in women who also have Crohn's disease while in remission. If you have Crohn's and painful periods, this may help you find a safer option.
Chapel Hill, North CarolinaAges 18–44 - NCT06863636RecruitingPhase 3
Combination painkiller vs celecoxib for osteoarthritis flare-ups
This study tests whether a combination of two pain relievers (celecoxib and acetaminophen) works better than celecoxib alone for sudden, severe osteoarthritis pain in the knee or hip.
Mexico CityAges 40 years+ - NCT07225634RecruitingPhase 3
Combogesic IV for acute pain in children ages 2-17
This trial tests a pain medicine given through an IV for children who are in the hospital with sudden (acute) pain, like after surgery or an injury. It aims to see if it helps control pain and is safe.
BudapestAges 2–16 - NCT07200544RecruitingPhase 4
Meloxicam for skin cancer surgery pain
This study tests if meloxicam, an anti-inflammatory painkiller, helps control pain after Mohs surgery for skin cancer. It aims to reduce the need for stronger opioid pain medicines.
Oklahoma City, OklahomaAges 18–110 - NCT07101445RecruitingPhase 4
Comparing steroids to prevent reactions to motixafortide in multiple myeloma
This trial tests two different steroid medicines (methylprednisolone and dexamethasone) to see which works better at preventing side effects from motixafortide, a drug used to help collect stem cells for a stem cell transplant in people with multiple myeloma.
Atlanta, GeorgiaAges 18 years+ - NCT07022496RecruitingPhase 4
Can oral caffeine help with acute migraine attacks?
This trial tests whether taking caffeine by mouth can reduce the severity of a migraine attack when it happens. It may offer a simple, at-home option for people with different types of migraine.
CairoAges 18–60 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06861920RecruitingPhase 4
NSAID use for painful periods to prevent chronic pelvic pain
This study tests whether using NSAIDs (like naproxen) for painful periods can help prevent chronic pelvic pain later on. It's for people with regular, painful periods who are otherwise healthy.
Evanston, IllinoisAges 18–35 - NCT06824467RecruitingPhase 3
Maintenance Therapy Study for Recurrent Ovarian Cancer
This study tests a new maintenance treatment (sacituzumab tirumotecan) versus standard care for people with ovarian cancer that has come back after responding to platinum-based chemotherapy. The goal is to see if it can keep the cancer from growing longer and improve quality of life.
Birmingham, AlabamaAges 18 years+ - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20
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Common questions
- Are there clinical trials for acetaminophen?
- Yes. Clin2 currently lists 65 recruiting acetaminophen studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acetaminophen trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acetaminophen trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.