Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 654 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05804318Recruiting
Adaptive daily radiation for low- and intermediate-risk prostate cancer
This trial tests a radiation plan that is adjusted every day using your own scans to better target prostate cancer. It may help reduce side effects while still treating the cancer effectively in men with lower- or intermediate-risk disease.
Duarte, CaliforniaAges 18 years+ - NCT05814913Recruiting
Culturally adapted therapy for early psychosis with caregiver support
This study tests culturally adapted talk-therapy to help people who are in the early stage of psychosis. It also involves a family member or caregiver, which may make the support at home easier and more consistent.
Karachi, SindhAges 18 years+ - NCT05838235Recruiting
Exercise program for kids with Marfan syndrome
This trial studies an adapted physical activity (exercise) program to support effort rehabilitation in children and teens with Marfan syndrome. It may help safely improve activity and fitness while monitoring heart-related risks.
ToulouseAges 7–17 - NCT05880667RecruitingPhase 1
Adaptive focused radiation for belly and pelvic cancer spread
This Phase 1 study tests an “adaptive” form of focused radiation (SBRT) for cancers that have spread in the abdomen or pelvis. It aims to treat metastatic tumor spots safely while adjusting the plan as needed during treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05883800Recruiting
Total treatment with tailored radiation for advanced rectal cancer
This study tests a “total neoadjuvant” approach—chemotherapy first, then radiation—using adaptive (tailored) radiation planning for people with locally advanced rectal cancer. It may help improve tumor control while adjusting the radiation based on how your cancer and anatomy respond.
BergenAges 18 years+ - NCT05884632Recruiting
Personalized daily radiation for prostate cancer after surgery
This trial studies a “daily adaptive” way of planning and delivering radiation after prostate surgery to treat prostate cancer that is coming back locally. It may help target the tumor more precisely while limiting radiation to healthy tissue.
Negrar, VeronaAges 18–80 - NCT05909111Recruiting
Testing a radiation plan for cervical cancer using MRI guidance
This feasibility study tests whether an MRI-guided radiation approach can be used safely and practically for people with certain stages of cervical cancer. It’s meant to help doctors plan radiation more accurately, while checking whether the treatment process works well.
AvignonAges 18 years+ - NCT05927389Recruiting
Exercise program for kids with osteogenesis imperfecta
This trial tests an adapted physical activity program to help children and teenagers rebuild strength and improve effort/fitness. It may be helpful if you want a tailored exercise approach that is safe for osteogenesis imperfecta.
MontpellierAges 7–18 - NCT05959837Recruiting
Testing an adapted rower for people with spinal cord injury
This trial is testing whether an adapted rowing machine works well and is safe for people with spinal cord injuries. You may be able to take part if you use a wheelchair, can row with your arms, and are medically cleared to exercise.
Columbia, South CarolinaAges 18 years+ - NCT05981664Recruiting
Can adaptive gaming help kids with arm differences?
This study explores whether playing video games with adapted controls can help children aged 7 to 17 who have a missing or different arm or hand. It tests how fun and useful these games are for improving movement and daily life.
Winnipeg, ManitobaAges 7–17 - NCT06003725Recruiting
Drug treatment for Black youth on probation
This study is testing a drug treatment program that is made for Black youth involved with the justice system. It aims to see if a more culturally fitting approach can help reduce substance use and related problems.
San Francisco, CaliforniaAges 13–17 - NCT06053320Recruiting
Stroke rehab study using brain stimulation and movement training
This study tests whether a type of brain stimulation combined with movement training can help people who have had a right-side stroke improve their arm and hand function. It also includes healthy adults to compare results.
Atlanta, GeorgiaAges 18–90 - NCT06054542Recruiting
Digital eye strain questionnaire Turkish study
This study tests a Turkish version of a questionnaire about digital eye strain. It is for people aged 18–65 who use digital devices for at least two hours a day.
AntalyaAges 18–65 - NCT06116019Recruiting
Online adaptive radiotherapy for cancer patients
This trial tests a new radiation therapy machine that adjusts the radiation plan in real-time based on changes in your body. It may help make treatment more precise and reduce side effects.
BerlinAges 18 years+ - NCT06201884RecruitingPhase 2
Walking program for older patients after cancer surgery
This study tests whether a special walking program (using a platform) can help older patients recover better after cancer surgery. If you are 65 or older and can walk on the platform for 10 minutes, you might be eligible.
CaenAges 65 years+ - NCT06325046Recruiting
Adaptive radiation therapy for localized prostate cancer
This trial tests a type of radiation that adapts to your body's changes during treatment. It is for men with low- to intermediate-risk prostate cancer that hasn't spread.
Albert Lea, MinnesotaAges 18 years+ - NCT07252206Recruiting
Culturally adapted CBT for Black people with psychosis
This study offers a talking therapy called culturally adapted cognitive behavioral therapy for psychosis (CBTp) for Black people in the UK who have schizophrenia or related conditions. It aims to see if this approach is helpful and acceptable, and you may join if you are over 16, identify with a Black background, and are not in a current crisis.
ManchesterAges 16 years+ - NCT06330779Recruiting
Trauma-adapted yoga for teens with PTSD or ADHD
This trial tests if a special yoga program helps teenagers with PTSD or ADHD feel better. It is designed to be safe and supportive for their mental health.
GothenburgAges 12–18 - NCT06355050Recruiting
Short, intense radiation for prostate cancer
This trial tests a very short course of daily radiation that adapts to your body's changes. It aims to be just as effective as standard treatment but more convenient.
JenaAges 18–120 - NCT06444659Recruiting
Exercise study for students with intellectual disabilities
This study tests whether a special exercise program can improve fitness and health in students with intellectual disabilities. It is designed for students who are not already involved in other physical activities outside of school sports.
ChangshaAges 13–18 - NCT06455592Recruiting
Can physical activity improve sleep in children with cancer?
This study tests whether a personalized physical activity program (called APA) can help children with blood cancer sleep better. If your child is between 5 and 16 and currently on cancer treatment, this program might be a good fit.
Clermont-FerrandAges 5–16 - NCT06484244Recruiting
Walking and balance in memory loss
This study looks at how older adults with mild cognitive impairment or Alzheimer's disease adapt their walking. It aims to understand walking and balance to help people stay mobile and safe longer.
Atlanta, GeorgiaAges 50–90 - NCT06507072Recruiting
Adaptive rock climbing for kids with arm differences
This study tests whether adaptive rock climbing can help children with arm or hand differences improve their physical function and confidence. It aims to find fun and effective ways to support your child's development.
Los Angeles, CaliforniaAges 6–16 - NCT06546696Recruiting
Obesity support program for children and families
This trial offers a 6-month program to help children ages 6–11 with obesity and their parents adopt healthier habits, including exercise and nutrition. It takes place at community centers in Middle Tennessee and provides online training.
Nashville, TennesseeAges 6–12
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 654 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.