Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 646 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06185062Recruiting
Pelvic cancer registry for online adapted radiotherapy
This study collects data from patients receiving a type of radiation therapy that is adjusted in real-time. It aims to learn more about how well this approach works for pelvic and chest tumors.
GöttingenAges 18 years+ - NCT06041555Recruiting
MRI-guided radiotherapy study for five cancer types
This study collects MRI scans and treatment data from patients getting MRI-guided radiotherapy for certain cancers. It aims to improve radiation treatment planning using imaging and biological information.
LyonAges 18 years+ - NCT06306521Recruiting
Newborn screening for hundreds of genetic diseases by genome sequencing
This research study tests a new way to screen newborns for hundreds of genetic diseases using a sample of their blood or saliva. It aims to find conditions early so your baby can get the right care sooner.
San Diego, CaliforniaAges 1 day–4 weeks - NCT06240637Recruiting
Telemonitoring for starting home ventilator
This study tests whether using a remote monitoring system (telemonitoring) helps people adjust better to a new home ventilator. It is for people with long-term breathing problems who are starting a ventilator for the first time.
BarcelonaAges 18 years+ - NCT06345287RecruitingPhase 2
Adaptive radiotherapy after immunotherapy for head and neck cancer
This trial tests a personalized radiotherapy approach after a few rounds of chemo-immunotherapy for people with HPV-negative head and neck cancer. It aims to adjust the radiation dose based on how the tumor responds, possibly reducing side effects while still controlling the cancer.
BeijingAges 18–75 - NCT05525962Recruiting
Study factors that affect development in foster children
This study looks at how different stress and support factors may influence how children and teens grow and cope while they are involved with child protective services. It may help clinicians understand what supports work best for children in care.
CanteleuAges Up to 16 years - NCT05080556RecruitingPhase 2
Adaptive chemotherapy for ovarian cancer after platinum and PARP
This trial tests a personalized (adaptive) chemotherapy plan for people with certain types of ovarian/fallopian tube/peritoneal cancer who already had platinum chemotherapy and a PARP inhibitor. It’s for patients whose cancer came back after (or still responds to) prior platinum treatment and may help delay disease progression.
LondonAges 18 years+ - NCT06346639Recruiting
Hot and cold training for 16 days
This study tests how a 16-day program of alternating hot and cold exposure affects your body's ability to adapt and improve health markers like stress and recovery. It is for healthy, young adults who are not athletes and do not take supplements or medications.
KaunasAges 18–45 - NCT06361043Recruiting
Adaptive radiation therapy for esophageal cancer
This study tests a new, more precise type of radiation therapy for esophageal cancer that adjusts the treatment in real time using a special CT scan. It aims to deliver a stronger dose to the tumor while sparing healthy tissue, which could improve outcomes.
BernAges 18 years+ - NCT04857775Recruiting
Test a parent-training app for infants and toddlers
This study tests a web and mobile program that supports parents with training for their child’s early development. It uses parent sessions over about 10–12 weeks and includes a small blood sample to help researchers measure effects.
Calgary, AlbertaAges Any age - NCT06214026Recruiting
Study of a new prosthetic foot for better walking
This study tests a new type of prosthetic foot designed to help people walk more naturally. If you use a prosthetic foot and can walk short distances, this trial may help you move better.
Tampa, FloridaAges 16 years+ - NCT07847073RecruitingPhase 4
Comparing eye drops for glaucoma and their effect on the optic nerve
This trial tests two eye drops—Rhopressa (netarsudil) and timolol—at lowering eye pressure in people with open-angle glaucoma. The study uses a special camera to see if treatment helps protect the nerve cells in the back of the eye.
Bloomington, IndianaAges 18 years+ - NCT07829848Recruiting
Skip extra radiation for breast cancer patients who respond well to treatment
This trial tests whether women and men with advanced, non-metastatic breast cancer can safely skip an extra radiation boost to the lymph nodes if their tumors respond well to pre-surgery chemotherapy or targeted therapy. The goal is to reduce side effects while keeping cancer control.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05029531RecruitingPhase 3
Immuno-chemotherapy for infants with B-lineage ALL
This trial tests a combination of medicines (immunotherapy plus chemotherapy) in babies diagnosed with a type of leukemia called B-lineage acute lymphoblastic leukemia (ALL). It aims to improve how well treatment works and is delivered safely in very young children.
Moscow, Samory-Mashela,1Ages 1 day–12 months - NCT07818980Recruiting
An online pain management program for Canadian veterans
This study is testing an online pain management program designed for Canadian veterans. If you have chronic pain, joining could help you learn ways to manage pain from home.
Toronto, OntarioAges 18–80 - NCT07822997Recruiting
Quality of Life Questionnaire for Pulmonary Hypertension in Brazil
This study is testing a questionnaire (EMPHASIS-10) to measure quality of life in people with pulmonary hypertension. The goal is to adapt it for Brazilian Portuguese speakers so doctors can better understand how the disease affects daily life.
Porto AlegreAges 18 years+ - NCT06461481Recruiting
Follow-up strategies for de-escalating multiple sclerosis treatment
This study tests different ways of monitoring people with relapsing-remitting MS who are reducing or stopping their medication. It aims to find the safest follow-up approach and may help guide future treatment decisions for those with stable disease.
DüsseldorfAges 18 years+ - NCT06301425Recruiting
Transplant study for high-risk AML based on MRD response
This trial tests whether adjusting a stem cell transplant (allo-HSCT) based on a marker called MRD (minimal residual disease) improves outcomes for people with a high-risk type of acute myeloid leukemia (AML). It's for those who are newly diagnosed, between 16 and 65, and have early remission after 1 or 2 rounds of chemotherapy.
BeijingAges 16–65 - NCT02735707RecruitingPhase 3
Adaptive trial for severe pneumonia care in intensive care
This study tests ways to improve treatment for adults with severe pneumonia that lands them in the ICU, adjusting the plan as results come in. It may help your care team find better treatments for lung infection and breathing/heart support needs.
Jacksonville, FloridaAges 18 years+ - NCT07803068Recruiting
Ashwagandha supplement and weight training for strength and focus
This study tests whether taking ashwagandha, an herb often used for stress, for 12 weeks can boost strength, brain function, and stress resilience when combined with your regular weight training. It's for healthy, active men who already lift weights regularly.
Gdansk, Pomeranian VoivodeshipAges 25–40 - NCT07796971Recruiting
Exercise in low vs normal oxygen for weight and gut health
This study tests two exercise programs—one in low oxygen, one in normal oxygen—to see which is better at reducing body fat and improving gut health in adults aged 50–75 who are overweight or obese. You'll do high-intensity interval training (short bursts of intense exercise) and we'll monitor your results over time.
Bellerive-sur-AllierAges 50–75 - NCT07798674Recruiting
Natural history study for ataxias and spastic paraplegias
This study tracks how ataxias and related movement disorders progress over time. By joining, you help researchers learn more about these conditions and prepare for future treatments.
InnsbruckAges 5 years+ - NCT07798271Recruiting
Optimizing deep brain stimulation for Parkinson's disease
This study is for people with Parkinson's disease who already have a deep brain stimulator (a device that sends electrical pulses to the brain) and still have motor fluctuations (times when symptoms come and go). The researchers want to see if adapting the device's settings can better control symptoms than the current standard settings.
Davis, CaliforniaAges 18 years+ - NCT07789639RecruitingPhase 4
Sunscreen effectiveness study on back skin
This study tests two sunscreen products to see how well they protect the skin from sun damage. Participants will have a small area on their back treated and then exposed to a controlled amount of UV light to measure the products' effectiveness.
Winston-Salem, North CarolinaAges 18–75
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 646 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.