Clinical trials
Adaptation clinical trials
Below are recruiting adaptation clinical trials, each written for real people, not researchers. We’re tracking 646 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04942717Recruiting
Talking about health values with Spanish or English-speaking patients
This study tests an approach for discussing and sharing what patients value about their health, and adapting it for Latinx communities. It involves separate interviews with patients, families/caregivers, and oncology clinicians to improve how the intervention works and is understood.
New York, New YorkAges 21 years+ - NCT04020276Recruiting
Adaptive MRI radiation for liver metastases
This study tests a radiation treatment that uses real-time MRI (an imaging scan) to guide the dose for liver metastases. It may help control tumors while aiming to better protect nearby healthy liver tissue.
Madison, WisconsinAges 18 years+ - NCT04280458Recruiting
Intensive movement and thinking rehab for children with severe disabilities
This trial tests an intensive rehabilitation program to improve both movement abilities and daily function in children with severe, long-term disability due to early brain injury. It may help children gain better adaptive skills and independence through structured therapy.
Hyères, VarAges 4–13 - NCT06825091RecruitingPhase 3
Comparing new SBRT to standard radiation for prostate cancer
This trial compares a newer, more precise type of radiation (adaptive SBRT) with standard image-guided radiation for prostate cancer. It aims to see if the newer approach is better at targeting the tumor while reducing side effects.
Toronto, OntarioAges 18 years+ - NCT04724928RecruitingPhase 2
PET-CT scan to guide bladder cancer treatment decisions
This Phase 2 study checks whether an FDG PET-CT scan can help doctors better predict bladder cancer risk and adjust treatment. You may still get standard bladder cancer care, but the study uses the scan results to help decide how aggressive treatment should be.
GhentAges 18 years+ - NCT05301283RecruitingPhase 2
Adaptive radiation therapy before surgery for soft-tissue sarcoma
This trial tests a personalized (“adaptive”) radiation plan before surgery for high-grade soft-tissue sarcoma that can be removed. It may help shrink the tumor and improve how well surgery can treat the cancer.
Tampa, FloridaAges 18 years+ - NCT06815289Recruiting
MR-guided radiation for hard-to-treat central lung tumors
This trial tests a specialized radiation therapy that uses daily MRI scans to precisely target lung tumors located near the windpipe or esophagus. It aims to improve treatment accuracy while reducing side effects.
ZurichAges 18 years+ - NCT06467292Recruiting
Speech Learning and Memory Study
This study looks at how people learn and remember speech movements. It may help explain how we improve speaking skills over time.
New Haven, ConnecticutAges 18–40 - NCT06204315RecruitingPhase 2
Spine radiosurgery for spinal cord compression
This trial tests a precise radiation technique for people whose spinal tumors are very close to the spinal cord or nerves. It aims to safely give higher radiation doses while limiting damage to the cord.
Houston, TexasAges 18 years+ - NCT06468046Recruiting
Empowered Mom: A mental health program for migrant mothers
This study tests a new program called 'Mama Empoderada' (Empowered Mom) to help prevent depression and anxiety in migrant mothers who have young children. If you join, you'll learn skills to support your mental health and bond with your child.
Tijuana, Estado de Baja CaliforniaAges 18–99 - NCT06464432Recruiting
Complex PTSD treatment test for Egyptians in cities
This study is testing a therapy for Complex PTSD that has been adapted to fit Egyptian culture. It aims to see if the treatment helps people with severe trauma and provides a better way to diagnose the condition in Egypt.
CairoAges 18 years+ - NCT07434531Enrolling by invitation
Emotional learning program for Pakistani adolescents
This trial tests a special program designed to help young students in Pakistan learn how to understand and manage their emotions, build better relationships, and handle everyday challenges. It aims to see if this program works and if students find it helpful.
IslamabadAges 10–14 - NCT06356558Recruiting
Making recovery programs easier for patients with limited health literacy
This study is testing ways to improve recovery programs for patients who may have trouble understanding health information. It aims to make these programs easier to follow, so patients can have better recovery after surgery.
Birmingham, AlabamaAges 18 years+ - NCT07641621Recruiting
Chiropractic Ankle Treatment and Jump Performance Study
This study tests whether chiropractic ankle manipulation improves how high and powerfully you can jump. Researchers will work with recreationally active adults to see if this treatment affects athletic performance.
Seneca Falls, New YorkAges 18–35 - NCT06408688RecruitingPhase 4
Mistletoe extract added to immunotherapy for advanced solid tumors
This trial tests whether adding mistletoe extract (Iscador) to standard immunotherapy can make the treatment safer and boost the immune system's response against advanced solid tumors (excluding skin cancer). If you are already receiving or about to start a checkpoint inhibitor, this study may help understand if the combination works better.
BadenAges 18 years+ - NCT07314099Recruiting
Study of the Breizh Fabribus program for assistive devices
This study looks at the Breizh Fabribus program, which helps people get personalized assistive devices. It aims to see if the program helps improve your daily life.
Brest, FinistèreAges Any age - NCT06214026Recruiting
Study of a new prosthetic foot for better walking
This study tests a new type of prosthetic foot designed to help people walk more naturally. If you use a prosthetic foot and can walk short distances, this trial may help you move better.
Tampa, FloridaAges 16 years+ - NCT07616453RecruitingPhase 2
New Drug Plus Hormone Therapy for Hormone-Responsive Breast Cancer
This trial tests whether a new drug called culmerciclib, combined with hormone therapy, works better than hormone therapy alone for early-stage breast cancer that grows quickly and responds to estrogen. The goal is to shrink tumors before surgery and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07330921Recruiting
Testing a new 3D seating system for kids with motor issues
This trial is testing a new 3D seating system designed for children with motor control problems. It aims to see if this system helps them sit better and be more comfortable.
Zaragoza, ZaragozaAges 2–6 - NCT02852213RecruitingPhase 1
Dose-check study for children with AADC deficiency using brain surgery
This Phase 1 trial tests how safe different treatment doses are for children with AADC deficiency, using MRI-guided brain surgery. It may help improve movement and developmental progress after standard medicines did not work well enough.
San Francisco, CaliforniaAges 2 years+ - NCT07613333Recruiting
Exercise Program for New Mothers
This study tests an exercise program designed for women who have given birth within the past 2 years. Researchers want to learn how exercise affects energy levels and overall health after pregnancy.
Waukesha, WisconsinAges 18 years+ - NCT07616427RecruitingPhase 2
New drug plus hormone therapy for HER2-positive breast cancer
This study tests a new drug called fovinaciclib combined with hormone therapy and HER2-targeting drugs for early-stage breast cancer that has specific markers (HR-positive and HER2-positive). The goal is to shrink tumors before surgery and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT07585357Recruiting
Mobile app to help young smokers quit
This study tests a smartphone app that uses your location and daily habits to help you quit smoking. Researchers will send you personalized tips and support for 44 days to see if this approach helps you successfully stop smoking.
Baltimore, MarylandAges 18–40 - NCT07109076Recruiting
Immediate skin contact after C-section and baby's heart rate
This study looks at how holding your baby skin-to-skin right after a planned C-section affects their heart rate patterns. It may help understand benefits for you and your newborn.
Ljubljana, LjubljanaAges birth+
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Common questions
- Are there clinical trials for adaptation?
- Yes. Clin2 currently lists 646 recruiting adaptation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.