Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,090 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05831033RecruitingEarly Phase 1
Your own immune T-cells to treat advanced solid tumors
This early-phase study tests a treatment made from your own tumor-fighting immune cells (TIL cells) for advanced solid cancers that have worsened or no longer respond to standard therapy. The main goal is to learn whether it is safe and whether it can shrink tumors for people who have limited options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07753343Recruiting
Study of high-risk kidney cancer patients
This study looks at patients with kidney cancer that hasn't spread and is considered high-risk. It uses a registry to learn more about these patients to improve future care.
BordeauxAges 18 years+ - NCT07755449RecruitingPhase 2
Targeted radiation for head and neck cancer after surgery
This trial tests a new way of giving radiation therapy only to the side of the neck that needs it, which may reduce side effects while still preventing cancer from coming back. It is for people who have had surgery for head and neck cancer and have not had the cancer spread to the lymph nodes.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07755761Recruiting
Tube surgery for hard-to-treat glaucoma
This study tests a new tube-based surgery to lower eye pressure in people with advanced or difficult-to-treat open-angle glaucoma. The goal is to see if this surgery works better than standard care for controlling pressure and preserving vision.
BanhāAges 18 years+ - NCT07755540RecruitingPhase 2
Group music therapy for chronic pain in active duty service members
This study tests whether participating in group music therapy sessions can help active duty service members manage chronic pain. It aims to see if music therapy can improve pain symptoms and quality of life.
Anchorage, AlaskaAges 18–64 - NCT07750067RecruitingPhase 2
Combination therapy for advanced melanoma with NRAS mutation
This trial tests a combination of three drugs (tunlametinib, pucotenlimab, and hydroxychloroquine) for people with advanced melanoma that has a specific genetic change called NRAS. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Guangzhou, GuangdongAges 18 years+ - NCT06510660RecruitingPhase 2
Immunotherapy and Chemoradiation for Advanced Esophageal Cancer
This trial tests a combination of immunotherapy (adebrelimab) plus standard chemotherapy and radiation for people with advanced esophageal cancer that cannot be removed by surgery. The goal is to see if adding the immunotherapy before and during chemoradiation helps control the cancer better.
Fuzhou, FujianAges 18–70 - NCT06525298RecruitingPhase 1/Phase 2
Study of EIS-12656 for solid tumors with DNA repair defects
This trial tests a new drug, EIS-12656, alone or with other treatments, for solid tumors that have specific DNA repair problems called homologous recombination deficiency. It may be an option if your cancer has not responded to prior treatments.
Houston, TexasAges 18 years+ - NCT06590142Recruiting
Studying bowel tissue for future Hirschsprung's treatments
This trial collects leftover intestine tissue from children having bowel surgery to help develop future treatments using a child's own cells. It aims to find better ways to repair the bowel without needing donor tissue.
Liverpool, MerseysideAges birth–15 years - NCT06589544Recruiting
Virtual reality and brain stimulation for depression in cancer patients
This trial tests whether combining virtual reality therapy with transcranial magnetic stimulation (a non-invasive brain treatment) can help reduce depression in people who have had cancer in the last 5 years. It aims to improve mood without using medication.
Ferrara, FEAges 18–100 - NCT06589609RecruitingPhase 1
FluBHPVE6E7 immunotherapy for HPV16-positive oropharyngeal cancer
This trial tests a new immunotherapy called FluBHPVE6E7 for people with HPV16-positive oropharyngeal cancer that has not spread to distant parts of the body. The treatment is given directly into the tumor to help the immune system fight the cancer.
ViennaAges 18–65 - NCT06344052RecruitingPhase 2
SP-002 with Vismodegib for Advanced Basal Cell Cancer
This trial tests a new drug (SP-002) combined with vismodegib for people with locally advanced basal cell carcinoma, a type of skin cancer that can't be treated with surgery or has come back after surgery. The goal is to see if this combination is safe and effective.
Phoenix, ArizonaAges 18 years+ - NCT07746791Recruiting
Mobile health program for first-year female university students in Ethiopia
This study uses mobile technology to improve the health of first-year female university students in Ethiopia. If you are a first-year female student with a mobile phone, you may be able to join.
Bahir Dar, AmharaAges Any age - NCT06607796RecruitingPhase 3
PTS injection for stage 4 lung cancer without gene mutations
This trial tests injecting a drug called PTS directly into lung tumors for people with stage 4 non-small cell lung cancer that doesn't have certain gene changes. It is for patients whose tumors have stayed stable after first-line treatment and are located in a small area of the outer lung.
Guangzhou, GuangdongAges 18–75 - NCT05142150Recruiting
Care and expectations study for advanced gynecologic cancer
This trial looks at what patients with advanced gynecologic cancer expect from care, and how well their care needs are being met. It uses questionnaires to learn what support is most helpful, especially near the end of life.
OsloAges 18 years+ - NCT06623565Recruiting
Advanced imaging for extensive brain tumor removal
This trial uses advanced imaging to help surgeons remove as much of a malignant brain tumor as safely possible. It may be a good fit if you have a new diagnosis of glioblastoma or a certain astrocytoma and are healthy enough for surgery.
Amsterdam, North HollandAges 18 years+ - NCT05196334Recruiting
Testing pancreatic lab samples to guide future treatments
This study uses small pancreatic cancer samples grown in the lab to understand which treatments may work best for people with pancreatic cancer. It may help researchers better “profile” tumors so standard care can be matched to the most effective options.
Herlev, CopenhagenAges 18 years+ - NCT07726992RecruitingPhase 3
New drug plus BCG for high-risk bladder cancer
This study tests a new immunotherapy drug (SHR-1501) combined with standard BCG therapy for people with a specific type of early bladder cancer (papillary-only, high-risk). The goal is to see if the combination helps prevent cancer from returning better than BCG alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07731750Recruiting
Smart pain treatment plan for chronic low back pain
This study tests a computer-based tool to help choose the best pain treatments for people with chronic low back pain. It compares different treatments to see which ones work best for each person.
Ann Arbor, MichiganAges 25 years+ - NCT07729683Recruiting
Testing wakame seaweed for kidney disease patients
This study tests whether eating a daily dose of wakame seaweed can lower certain waste products (AGEs) in your blood that build up with kidney disease. It's for people with moderate chronic kidney disease who are already on standard protective medications.
La RochelleAges 18–90 - NCT07725601Recruiting
VNS dosing algorithm for epilepsy
This trial tests a new way to adjust the settings on a Vagus Nerve Stimulator (VNS) to better control seizures in people with epilepsy. It is for those who are already getting a VNS implanted to treat their seizures.
Augusta, GeorgiaAges 18–75 - NCT06632093Recruiting
Combination therapy for advanced liver cancer after standard treatment fails
This trial tests a triple combination of liver-directed chemotherapy (HAIC) plus immunotherapy (PD-1 inhibitor) and targeted therapy (Lenvatinib) for people with advanced liver cancer that has spread into the portal vein and who have already tried and failed standard treatments.
Shenyang, LiaoningAges 18–75 - NCT07718165RecruitingPhase 1
Study of ABSK211 for advanced solid tumors with KRAS changes
This trial tests a new drug called ABSK211 in people with advanced solid tumors that have a change in the KRAS gene. The goal is to see if the drug is safe and works against the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06602011Recruiting
Triple therapy for advanced liver cancer with bile duct invasion
This study tests a combination of three treatments—TACE (a procedure that blocks blood flow to the tumor), lenvatinib (a targeted therapy pill), and tislelizumab (an immunotherapy)—for people with liver cancer that has spread into the bile ducts and can't be removed by surgery. The goal is to see if this triple therapy helps shrink or control the cancer.
Fuzhou, FujianAges 18–75
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,090 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.