Clinical trials
Advanced or Metastatic Non-small Cell Lung Cancer clinical trials
Below are recruiting advanced or metastatic non-small cell lung cancer clinical trials, each written for real people, not researchers. We’re tracking 5,553 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07627334Recruiting
Personalized drug testing for newly diagnosed brain tumors
This trial tests whether customized drug screening on your tumor cells can help doctors choose the best treatment for you. Your tumor cells will be grown in the lab and tested against different drugs to find what works best, combined with short-course radiation therapy.
Vienna, State of ViennaAges Any age - NCT06671353Recruiting
Video decision support for advance care planning in frail older adults
This trial tests if watching a video helps older adults with frailty make informed decisions about future medical care. You may be able to join if you are 65 or older, have been diagnosed with frailty, and can watch a video and sign a consent form.
TaipeiAges 65 years+ - NCT06245694Recruiting
Emergency room study for neurological deficits
This trial uses advanced data analysis to help doctors in the emergency room better predict and treat neurological problems like stroke or brain injury. It aims to improve care for all adults who come to the ER with these issues.
ViennaAges 18–120 - NCT06117566RecruitingPhase 1/Phase 2
WX390 plus Toripalimab for advanced solid tumors
This trial tests a combination of two investigational drugs, WX390 and Toripalimab, for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if this combination can shrink tumors or slow their growth.
Changchun, JilinAges 18 years+ - NCT05667194RecruitingPhase 1
Early study of KH617 for advanced brain and solid tumors
This Phase 1 trial tests KH617, a new treatment, in adults with advanced cancers to see if it can be given safely and whether it shows signs of benefit. It is especially focused on tumors that have few or no standard treatment options, including certain brain tumor recurrences.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07619417Enrolling by invitation
Electric pulse ablation for pancreatic growths
This trial uses a special endoscopic tool to deliver electric pulses to abnormal growths in the pancreas. It may help people who cannot have surgery for these growths.
Columbus, OhioAges 18 years+ - NCT07613502Recruiting
Bio Leg: Advancing Mobility (BAM)
This study tests a new prosthetic leg designed to help people with above-knee amputations walk better. It may be a good fit if you already use a C-leg and can walk with a single point cane.
Jacksonville, FloridaAges 40–70 - NCT07619144Recruiting
Improving Heart Pump Outcomes Using Advanced Data Analysis
This study examines detailed data from patients who received an Impella 5.5 heart pump to treat cardiogenic shock—a life-threatening condition where the heart cannot pump enough blood. Researchers use advanced computer analysis to understand what helps patients recover best.
ViennaAges 18 years+ - NCT07620041RecruitingPhase 1
Testing QLC5508, a new cancer drug, in advanced solid tumors
This early-stage trial tests QLC5508, an experimental cancer medication, in patients with advanced solid tumors that haven't responded to standard treatments. The study focuses on safety, how the drug moves through your body, and potential interactions with other medications.
Changchun, JilinAges 18 years+ - NCT05940311Recruiting
Blood test for melanoma with BRAF V600E mutation
This trial studies a very sensitive blood test to detect melanoma-related genetic changes in people with BRAF V600E. It may help track the disease more closely and guide care in advanced or high-risk situations.
RomeAges 18 years+ - NCT03976245RecruitingPhase 4
Tested new advanced treatment options for rheumatoid arthritis
This trial studies advanced medicines for rheumatoid arthritis (RA) in people whose RA is still active despite several standard treatments. It may help by testing whether a different advanced option can better control symptoms and joint inflammation.
London, OntarioAges 18 years+ - NCT07607769Recruiting
Tremelimumab and Durvalumab for Untreated Advanced Liver Cancer
This Italian study follows patients with advanced liver cancer (hepatocellular carcinoma) who receive a combination immunotherapy treatment called STRIDE for the first time. The trial tracks how well the treatment works, how it affects quality of life, and its safety in people with moderate to severe liver disease.
AnconaAges 18–100 - NCT07609329Recruiting
Nutritional Support Before Sarcoma Surgery
This study tests whether special nutritional supplements given before surgery for bone or soft tissue sarcoma (a type of cancer) can help your body heal better and recover faster. You'll take oral supplements for at least a week before your planned surgery.
BrnoAges Any age - NCT07608328RecruitingPhase 4
Azithromycin to Reduce Bronchiectasis Flare-Ups
This study tests whether a common antibiotic called azithromycin can help prevent flare-ups (sudden worsening) of bronchiectasis—a lung condition where airways become permanently enlarged and damaged. Patients will take azithromycin or a placebo for 12 months to see if it reduces how often they get sick.
AsyutAges 18 years+ - NCT06609863Recruiting
Triple therapy for large liver cancer tumors
This trial tests combining a special type of chemo delivered directly to the liver (dTACE-HAIC) with two immunotherapy drugs (bevacizumab and atezolizumab) for people with huge liver cancer tumors (10 cm or larger). The goal is to see if this combination can shrink tumors and improve outcomes.
Beijing, None SelectedAges 18–75 - NCT06713252Recruiting
Art therapy for stroke recovery
This study tests whether art therapy can help improve non-motor symptoms (like mood and thinking) during the early recovery phase after a stroke. Participants will attend art sessions while continuing their regular rehab.
Jiamusi, HeilongjiangAges 40–75 - NCT07602777RecruitingPhase 1/Phase 2
Testing Risvutatug Rezetecan for Advanced Bone and Soft Tissue Sarcomas
This study tests a new cancer drug called risvutatug rezetecan for people with advanced sarcomas (bone or soft tissue cancers) that have stopped responding to prior treatments. The drug works by delivering a cancer-killing agent directly to tumor cells.
West Valley City, UtahAges Any age - NCT07602049RecruitingPhase 2
Freezing Plus Immunotherapy for Advanced Soft Tissue Sarcoma
This trial combines cryoablation (a freezing technique to destroy tumors) with camrelizumab (an immunotherapy drug that helps your immune system fight cancer) for patients with advanced soft tissue sarcoma that hasn't responded to standard treatments. The goal is to see if this combination works better than current options.
Guangzhou, GuangdongAges 14–70 - NCT07599839Recruiting
Study of bronchiectasis severity and flare-up risk
This study helps doctors understand how severe your bronchiectasis is and predict when you might have flare-ups. You'll have routine tests over 12 months to help researchers learn more about this condition and improve future care.
Asyut, Asyut EgyptAges 18 years+ - NCT07599969Recruiting
Understanding bronchiectasis subtypes for better treatment
This study helps doctors identify different types of bronchiectasis (a lung disease where airways are permanently widened and damaged) to better understand how the disease develops and progresses. By following patients over time and collecting medical information, researchers hope to create a system that predicts which patients will worsen and need different treatments.
Asyut, Assiut EgyptAges 18 years+ - NCT05918445RecruitingPhase 1/Phase 2
PM8002 for advanced solid tumors that have stopped responding
This Phase 1/2 study tests PM8002 in people with advanced solid cancers to see if it can work and is safe. It may help if your cancer has measurable disease and you have not fully recovered from side effects of prior treatment.
BaojiAges 18–75 - NCT07589244RecruitingPhase 2/Phase 3
VRT106 with Camrelizumab and Apatinib for Advanced Liver Cancer
This study tests a combination of three drugs—VRT106 (a new oncolytic virus therapy), camrelizumab (an immune-boosting drug), and apatinib (a targeted cancer drug)—to treat advanced hepatocellular carcinoma (HCC), a type of liver cancer. The goal is to see if this combination works better than standard treatments.
Guangzhou, GuangdongAges 18–75 - NCT07586891Recruiting
Low-Branched-Chain Amino Acid Diet With Immunotherapy for Stage III Melanoma
This trial tests whether a special diet low in certain amino acids (building blocks of protein), combined with an immune-boosting antibody drug, can safely shrink stage III melanoma that has spread to lymph nodes. The goal is to see if this combination works better than standard treatment.
Xi'anAges 18–75 - NCT07586904RecruitingEarly Phase 1
New Immunotherapy Combination for Advanced Melanoma
This trial tests a combination of two drugs (cadonilimab and interferon) given before surgery to treat advanced melanoma that has spread to nearby lymph nodes or one distant site. The goal is to shrink tumors and improve chances of successful surgery and long-term survival.
Xi'anAges 18–75
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Common questions
- Are there clinical trials for advanced or metastatic non-small cell lung cancer?
- Yes. Clin2 currently lists 5,553 recruiting advanced or metastatic non-small cell lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic non-small cell lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic non-small cell lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Locally Advanced or Metastatic Non-small Cell Lung Cancer
- Metastatic Non-squamous Non Small Cell Lung Cancer
- Advanced Non-squamous Non-small-cell Lung Cancer
- NSCLC (Advanced Non-small Cell Lung Cancer)
- Non Small Cell Lung Cancer Metastatic
- Non Small Cell Lung Cancer
- Non-squamous Non-small Cell Lung Cancer
- Locally Advanced Non-Small Cell Lung Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.